Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.48 |
| ▸ | ITGAV | P06756 | 10/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650264 | 0.94 | NPY5R (0.52) | ITGB3ITGA2BITGAVNPY5RLMNA | |
| SCHEMBL7114722 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL4650967 | 0.94 | ITGB3 (0.44) | ITGB3ITGA2BITGAVNPY5RAVPR1B | |
| SCHEMBL4650222 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BITGAVF2TMPRSS6 | |
| SCHEMBL4650994 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BITGAVNPY5RF2 | |
| SCHEMBL4650241 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BITGAVNPY5RKMT2A | |
| SCHEMBL4651088 | 0.91 | MAPT (0.43) | ITGB3ITGA2BITGAVLMNAMAPT | |
| SCHEMBL4651118 | 0.90 | ITGB3 (0.42) | ITGB3ITGA2BITGAVF2LMNA | |
| SCHEMBL14066274 | 0.90 | MAPT (0.49) | ITGB3ITGA2BITGAVNPY5RLMNA | |
| SCHEMBL4651098 | 0.90 | HSD17B10 (0.45) | ITGB3ITGA2BITGAVNPY5RMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301474-B1 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2008-09-10 | — | — | EP | claimed |
| US-6586467-B2 | Tyrosine phosphatase inhibitors useful in the treatment or prevention of Type II Diabetes Mellitus | ARRAY BIOPHARMA INC. | 2003-07-01 | — | — | US | claimed |
| EP-1301474-A2 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | Array Biopharma Inc. (US) | 2003-04-16 | — | — | EP | claimed |
| US-20020040003-A1 | Preparation of phosphatase inhibitors | ARRAY BIOPHARMA INC. | 2002-04-04 | — | — | US | claimed |
| WO-2002004412-A2 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2002-01-17 | — | — | WO | claimed |
| EP-1301474-B1 | TYROSINE DERIVATIVES AS PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2008-09-10 | — | — | EP | disclosed |
| US-6586467-B2 | Tyrosine phosphatase inhibitors useful in the treatment or prevention of Type II Diabetes Mellitus | ARRAY BIOPHARMA INC. | 2003-07-01 | — | — | US | disclosed |
| US-20020040003-A1 | Preparation of phosphatase inhibitors | ARRAY BIOPHARMA INC. | 2002-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040003-A1 | Preparation of phosphatase inhibitors | PTPRS, PTPRO, PTPRR | ITGB3 3242/4885ITGA2B 2530/4885ITGAV 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.