Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300279 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| SCHEMBL300278 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| SCHEMBL4400451 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| SCHEMBL13482629 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| SCHEMBL4458272 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| SCHEMBL4458267 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| SCHEMBL1992431 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| SCHEMBL4400447 | 1.00 | ACE (0.49) | ACEL3MBTL1LMNAKMT2APOLB | |
| Hydrochloric Acid SCHEMBL5287673 | 0.98 | ACE (0.48) | ACEL3MBTL1LMNAKMT2APOLB | |
| Hydrochloric Acid SCHEMBL3536442 | 0.98 | ACE (0.48) | ACEL3MBTL1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963265-A1 | PROCESS FOR THE PREPARATION OF PERINDOPRIL AND SALTS THEREOF | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007062865-A1 | PROCESS FOR THE PREPARATION OF PERINDOPRIL AND SALTS THEREOF | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2007-06-07 | — | — | WO | disclosed |
| EP-1792896-A1 | Process for the preparation of perindopril and salts thereof | KRKA, tovarna zdravil, d.d., Novo mesto (SI) | 2007-06-06 | — | — | EP | disclosed |