SCHEMBL4650378

SCHEMBL4650378

CS(=O)(=O)CC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11651534 0.82
SCHEMBL3474802 0.73
Dapansutrile SCHEMBL9934796 0.73
SCHEMBL11583271 0.73
SCHEMBL597046 0.71 NLRP3 (0.50)
SCHEMBL4812116 0.71 CA1 (0.39)
SCHEMBL4819116 0.69
SCHEMBL119163 0.69
SCHEMBL4805970 0.69
SCHEMBL4817810 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070129383-A1 Substituted 2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivative and use thereof NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2007-06-07 US claimed
US-7108727-B2 Reactive dyes and the use thereof for dyeing substrates containing nucleophilic groups BASF AKTIENGELLSCHAFT (DE) 2006-09-19 US claimed
EP-1674454-A1 SUBSTITUTED 2-AMINO- 1,2,4 TRIAZOLO 1,5-a PYRIMIDINE DERIVATIVE AND USE THEREOF Nippon Kayaku Kabushiki Kaisha (JP) 2006-06-28 EP claimed
US-20030019055-A1 Reactive dye mixture DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-01-30 US claimed
EP-1196502-A2 REACTIVE DYE MIXTURES DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2002-04-17 EP claimed
WO-2001000736-A2 REACTIVE DYE MIXTURES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-04 WO claimed
US-5681937-A Reactive azo dyes with a coupling component from the aminonaphthalenesulfonic acid series BASF AKTIENGESELLSCHAFT (DE) 1997-10-28 US claimed
US-5384331-A Ketamine analogues for treatment of thrombocytopenia GENENTECH, INC. (US) 1995-01-24 US claimed
EP-0623343-A1 Ketamine analogues for the treatment of thrombocytopenia GENENTECH, INC. (US) 1994-11-09 EP claimed
US-5250732-A Influence replication, differentiation or maturation of platelet progenitor cells GENENTECH, INC. (US) 1993-10-05 US claimed
US-4960870-A DYEING WOOL, POLYAMIDES; FIBER REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1990-10-02 US claimed
US-4918183-A Monoazo dyes, process for their preparation, and the use thereof CIBA-GEIGY CORPORATION (US) 1990-04-17 US claimed
EP-0142104-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-01-03 EP claimed
EP-0144776-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-10-11 EP claimed
US-4813972-A USING LEVELING DYES, COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1989-03-21 US claimed
EP-0159962-B1 FIBRE-REACTIVE CHROMIUM OR COBALT COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1989-02-08 EP claimed
US-4678851-A FIBER-RACTIVE CIBA-GEIGY CORPORATION (US) 1987-07-07 US claimed
EP-0159962-A2 Fibre-reactive chromium or cobalt complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-30 EP claimed
EP-0144776-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP claimed
EP-0142104-A2 Fibre-reactive chromium complexes, their preparation and their use CIBA-GEIGY AG (CH) 1985-05-22 EP claimed