Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650518 | 0.91 | KMT2A (0.50) | KMT2AKDM4EPOLBALDH1A1HTT | |
| SCHEMBL4650312 | 0.87 | ALDH1A1 (0.47) | KMT2AKDM4EPOLBALDH1A1HTT | |
| SCHEMBL4649740 | 0.86 | ALDH1A1 (0.50) | KMT2AKDM4EPOLBALDH1A1HTT | |
| Water SCHEMBL4695201 | 0.85 | ALDH1A1 (0.49) | KMT2AKDM4EPOLBALDH1A1HTT | |
| SCHEMBL4650471 | 0.85 | ALDH1A1 (0.47) | KMT2AKDM4EPOLBALDH1A1HTT | |
| SCHEMBL27748718 | 0.84 | KMT2A (0.44) | KMT2AKDM4EPOLBALDH1A1HTT | |
| SCHEMBL4651312 | 0.84 | ALDH1A1 (0.50) | KMT2AKDM4EPOLBALDH1A1HTT | |
| SCHEMBL4650402 | 0.82 | POLB (0.52) | KMT2AKDM4EPOLBALDH1A1HTT | |
| SCHEMBL4650557 | 0.82 | KDM4E (0.53) | KMT2AKDM4EPOLBALDH1A1RAB9A | |
| SCHEMBL27748496 | 0.82 | KMT2A (0.44) | KMT2AKDM4EPOLBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101336236-A | Anthranilic acid derivatives useful in treating infection with hepatitis c virus | WYETH CORP (US) | 2008-12-31 | — | — | CN | claimed |
| EP-1966181-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2008-09-10 | — | — | EP | claimed |
| WO-2008051244-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2008-05-02 | — | — | WO | claimed |
| EP-1966181-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008051244-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |