Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650485 | 1.00 | CNR2 (0.52) | CNR2LMNATACR1KDM4EALDH1A1 | |
| SCHEMBL4650434 | 0.87 | CNR2 (0.56) | CNR2LMNATACR1KDM4EALDH1A1 | |
| SCHEMBL4468306 | 0.85 | CNR2 (0.56) | CNR2LMNATACR1KDM4EALDH1A1 | |
| SCHEMBL4465011 | 0.80 | CNR2 (0.59) | CNR2LMNAKDM4EALDH1A1ATM | |
| SCHEMBL4465004 | 0.80 | CNR2 (0.59) | CNR2LMNAKDM4EALDH1A1ATM | |
| SCHEMBL4650470 | 0.80 | CNR2 (0.52) | CNR2LMNATACR1MEN1KMT2A | |
| SCHEMBL4485570 | 0.79 | CNR2 (0.57) | CNR2LMNAKDM4EALDH1A1ATM | |
| SCHEMBL4471986 | 0.78 | CNR2 (0.54) | CNR2LMNAKDM4EALDH1A1ATM | |
| SCHEMBL4471991 | 0.78 | CNR2 (0.54) | CNR2LMNAKDM4EALDH1A1ATM | |
| SCHEMBL4481105 | 0.78 | CNR2 (0.54) | CNR2LMNAKDM4EALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |