Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650485 | 0.87 | CNR2 (0.52) | CNR2KDM4EATMALDH1A1TACR1 | |
| SCHEMBL4650403 | 0.87 | CNR2 (0.52) | CNR2KDM4EATMALDH1A1TACR1 | |
| SCHEMBL4489036 | 0.85 | CNR2 (0.64) | CNR2KDM4EATMALDH1A1TACR1 | |
| SCHEMBL4651291 | 0.80 | CNR2 (0.56) | CNR2TACR1MEN1KMT2AS1PR1 | |
| SCHEMBL4476107 | 0.79 | CNR2 (0.66) | CNR2KDM4EATMALDH1A1TACR1 | |
| SCHEMBL4468418 | 0.77 | CNR2 (0.64) | CNR2KDM4EATMALDH1A1MEN1 | |
| SCHEMBL4483088 | 0.77 | CNR2 (0.60) | CNR2KDM4EATMALDH1A1TACR1 | |
| SCHEMBL4481096 | 0.77 | CNR2 (0.60) | CNR2KDM4EATMALDH1A1TACR1 | |
| SCHEMBL4474249 | 0.76 | CNR2 (0.59) | CNR2KDM4EATMALDH1A1TACR1 | |
| SCHEMBL4480824 | 0.76 | CNR2 (0.59) | CNR2KDM4EATMALDH1A1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |