SCHEMBL4650646

SCHEMBL4650646

COC(CCOc1ccccc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.61
PPARA Q07869 10/20 0.61
PPARD Q03181 7/20 0.61
TDP1 Q9NUW8 1/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
PKM P14618 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MAPK1 P28482 1/20 0.46
ALOX5 P09917 1/20 0.46
ALDH1A1 P00352 1/20 0.46
RECQL P46063 1/20 0.46
HPGD P15428 1/20 0.46
KCNA3 P22001 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6200075 0.87 PPARG (0.51) PPARGPPARAPPARDTDP1MAPT
SCHEMBL28727724 0.84 PPARG (0.49) PPARGPPARAPPARDTDP1MAPT
SCHEMBL28082367 0.83 PPARA (0.63) PPARGPPARAPPARDTDP1
SCHEMBL4651822 0.82 PPARG (0.59) PPARGPPARAPPARDMAPTRAB9A
SCHEMBL5394822 0.81 PPARG (0.84) PPARGPPARAPPARD
SCHEMBL4993603 0.81 PPARG (0.46) PPARGPPARAPPARDTDP1MAPT
SCHEMBL5375774 0.80 PPARG (0.92) PPARGPPARAPPARD
SCHEMBL1805351 0.80 TDP1 (0.57) PPARGPPARATDP1MAPTRAB9A
SCHEMBL1716121 0.79 MAPK1 (0.53) PPARGPPARATDP1MAPTRAB9A
SCHEMBL38651328 0.78 MAPT (0.46) PPARGPPARAPPARDMAPTALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3983424-A1 A MANUFACTURING PROCESS FOR PEPTIDE AND PROTEIN PRODUCTION Mytide Therapeutics, Inc. (US) 2022-04-20 EP disclosed
EP-1971222-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2008-09-24 EP disclosed
WO-2007059066-A2 REDUCED SWEETNESS CONFECTIONARY COMPOSITIONS AND COATED/FILLED FOOD PRODUCTS GENERAL MILLS, INC. (US) 2007-05-24 WO disclosed