Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650539 | 0.89 | KDM4E (0.52) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL20471481 | 0.82 | KDM4E (0.74) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL19328 | 0.82 | PDE4D (0.65) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL15165757 | 0.81 | PDE4D (0.50) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL2084738 | 0.79 | SMN1; SMN2 (0.50) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL20583553 | 0.79 | PDE4D (0.49) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL4650523 | 0.79 | KDM4E (0.55) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL17777909 | 0.79 | KDM4E (0.55) | KDM4EMAPTPOLBKMT2APDE4D | |
| SCHEMBL4650593 | 0.77 | — | — | |
| SCHEMBL20471495 | 0.75 | KDM4E (0.50) | KDM4EMAPTPOLBKMT2APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965644-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007071900-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |