SCHEMBL465076

SCHEMBL465076

COc1ccc(Br)c(Br)c1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
NQO2 P16083 3/20 0.44
ERN1 O75460 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
CA14 Q9ULX7 2/20 0.39
CA4 P22748 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TUBB1 Q9H4B7 2/20 0.37
ACHE P22303 1/20 0.37
ALOX5 P09917 1/20 0.37
PTGS2 P35354 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10398173 0.89 CA2 (0.47) MAPTNPSR1NQO2ERN1KDM4E
SCHEMBL29800758 0.89 CA2 (0.47) MAPTNPSR1NQO2ERN1KDM4E
SCHEMBL8762135 0.80 NQO2 (0.43) MAPTNPSR1NQO2ERN1KDM4E
SCHEMBL9109330 0.80 TUBB1 (0.47) MAPTNPSR1NQO2ERN1KDM4E
SCHEMBL1628136 0.80 CA2 (0.54) MAPTNPSR1NQO2ERN1KDM4E
SCHEMBL8071106 0.80 NQO2 (0.43) MAPTNPSR1NQO2ERN1KDM4E
SCHEMBL19729185 0.78 MAPT (0.57) MAPTNPSR1NQO2ERN1KDM4E
SCHEMBL4190024 0.78 TDP1 (0.55) MAPTNPSR1ALDH1A1L3MBTL1TDP1
SCHEMBL29492146 0.78 TDP1 (0.55) MAPTNPSR1ALDH1A1L3MBTL1TDP1
SCHEMBL7930018 0.77 CA1 (0.50) MAPTNPSR1NQO2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5681875-A MOLDING MATERIALS; IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1997-10-28 US claimed
CN-105246968-B Thermoplastic resin composition and its manufacture method 东丽株式会社 2018-02-16 CN disclosed
CN-105073892-B Fire resistance polycarbonate composition 拜耳材料科学有限责任公司 2017-03-29 CN disclosed
CN-105246968-A Thermoplastic resin composition and method for producing same TORAY INDUSTRIES 2016-01-13 CN disclosed
EP-2961799-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITIONS Covestro LLC (US) 2016-01-06 EP disclosed
CN-105073892-A Flame-retardant polycarbonate compositions BAYER MATERIALSCIENCE AG 2015-11-18 CN disclosed
US-9145490-B2 Flame-retardant polycarbonate compositions BAYER MATERIALSCIENCE LLC (US) 2015-09-29 US disclosed
US-20150247024-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITIONS BAYER MATERIALSCIENCE LLC (US) 2015-09-03 US disclosed
WO-2014133933-A1 FLAME-RETARDANT POLYCARBONATE COMPOSITIONS BAYER MATERIALSCIENCE LLC (US) 2014-09-04 WO disclosed
EP-1854842-B1 STYRENE RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME TORAY INDUSTRIES (JP) 2012-01-11 EP disclosed
US-5681875-A MOLDING MATERIALS; IMPACT STRENGTH GENERAL ELECTRIC COMPANY (US) 1997-10-28 US disclosed
CN-1137542-A Flame retardant high impact polystyrene composition GEN ELECTRIC (US) 1996-12-11 CN disclosed
EP-0723992-A1 Flame retardant high impact polystyrene composition GENERAL ELECTRIC COMPANY (US) 1996-07-31 EP disclosed
US-5539036-A ABS TERPOLYMER, BROMINATED COMPOUND, ANTIMONY OXIDE, PTFE DRIP SUPPRESSANT, HOUSINGS FOR OFFICE MACHINES GENERAL ELECTRIC COMPANY (US) 1996-07-23 US disclosed
EP-0708133-A1 Tetrafluoroethylene polymer compositions and process for making flame retardant thermoplastic compositions utilizing the same GENERAL ELECTRIC COMPANY (US) 1996-04-24 EP disclosed
US-4810739-A AROMATIC POLYCARBONATE, ACRYLONITRILE-BUTADENE-STYRENE GRAFT COPOLYMER, POLYTETRAFLUOROETHYLENE BAYER AKTIENGESELLSCHAFT (DE) 1989-03-07 US disclosed
US-4742104-A CONTAINING EPOXIDE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1988-05-03 US disclosed
US-4596851-A Polycarbonates, graft polymer of ethylenically unsaturated monomer grafted onto rubber, thermoplastic resin, butadiene-acrylonitrile copolymer BAYER AKTIENGESELLSCHAFT (DE) 1986-06-24 US disclosed
US-4579906-A TETRAFLUOROETHYLENE POLYMER, FLAMEPROOFING SYNERGIST, ORGANIC HALOGEN COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1986-04-01 US disclosed
US-4563496-A ACRYLONITRILE-BUTADIENE-STYRENE BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed