SCHEMBL4650767

SCHEMBL4650767

CCCCCc1ccc(-c2c(C(=O)O)cccc2-c2ccc(C#N)c(F)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.55
RARA P10276 2/20 0.55
RARG P13631 1/20 0.55
AGTR1 P30556 1/20 0.42
AGTR2 P50052 1/20 0.42
BRS3 P32247 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
MTOR P42345 1/20 0.41
KMT2A Q03164 1/20 0.41
PLK1 P53350 2/20 0.40
LTB4R2 Q9NPC1 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8678448 0.85 RARB (0.47) RARBRARARARGAGTR1AGTR2
SCHEMBL7516262 0.84 RARB (0.60) RARBRARARARGAGTR1AGTR2
SCHEMBL8678083 0.82 LTB4R2 (0.43) RARBRARARARGBRS3LTB4R2
SCHEMBL9755559 0.81 TSHR (0.49) RARBRARARARG
SCHEMBL4651808 0.81 RARB (0.55) RARBRARARARGBRS3LTB4R2
SCHEMBL8676486 0.80 SYK (0.45) RARBRARARARGLTB4R2
SCHEMBL6269146 0.79 RARB (0.64) RARBRARARARGMEN1ALDH1A1
SCHEMBL14526076 0.78 TSHR (0.59) RARBRARARARG
SCHEMBL8678897 0.77 SYK (0.43) LTB4R2
SCHEMBL15783715 0.77 TSHR (0.52) RARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP claimed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US claimed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP claimed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US claimed
EP-1599562-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES Nemoptic (FR) 2005-11-30 EP claimed
US-20040188654-A1 Nematic liquid crystal mixtures for bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2004-09-30 US claimed
WO-2004077390-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2004-09-10 WO claimed
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP disclosed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US disclosed
US-7115307-B2 Nematic liquid crystal mixtures for bistable display device NEMOPTIC (FR) 2006-10-03 US disclosed
EP-1599562-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES Nemoptic (FR) 2005-11-30 EP disclosed
US-20040188654-A1 Nematic liquid crystal mixtures for bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2004-09-30 US disclosed
WO-2004077390-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2004-09-10 WO disclosed