Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | RARG | P13631 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377160 | 0.90 | RARB (0.45) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL4818894 | 0.90 | RARB (0.45) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL8380765 | 0.89 | RARB (0.46) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL14526076 | 0.88 | TSHR (0.59) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL15783715 | 0.87 | TSHR (0.52) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL15783717 | 0.87 | TSHR (0.61) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL9153223 | 0.86 | TSHR (0.50) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8153271 | 0.84 | TSHR (0.57) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL14526069 | 0.84 | TSHR (0.53) | TSHRHSD17B10RARBCYP11B1CYP11B2 | |
| SCHEMBL27507706 | 0.83 | CYP11B1 (0.47) | TSHRHSD17B10RARBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005029-A1 | ELECTRO-OPTICAL LIQUID CRYSTAL SYSTEM | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-18 | — | — | WO | disclosed |