SCHEMBL4650784

SCHEMBL4650784

CCCCCC1COC(c2ccc(C#N)cc2)OC1

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 3/20 0.46
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP2A6 P11509 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MGLL Q99685 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
TBXA2R P21731 1/20 0.33
CYP19A1 P11511 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1934965 1.00 GRM2 (0.46) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL9719633 0.99 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL9362811 0.99 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL5348257 0.99 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL10865557 0.99 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL8975343 0.99 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL11290099 0.99 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL9362814 0.99 GRM2 (0.48) GRM2TSHRHSD17B10CYP2A6ALDH1A1
SCHEMBL10637970 0.96 TSHR (0.47) GRM2TSHRHSD17B10ALDH1A1HRH3
SCHEMBL1934266 0.96 GRM2 (0.41) GRM2TSHRHSD17B10CYP2A6MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP claimed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US claimed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP claimed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US claimed
EP-1599562-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES Nemoptic (FR) 2005-11-30 EP claimed
US-20040188654-A1 Nematic liquid crystal mixtures for bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2004-09-30 US claimed
WO-2004077390-A2 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2004-09-10 WO claimed
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US claimed
US-5172256-A Liquid crystal variable color density lens and eye protective devices incorporating the same LIQUID CRYSTAL OPTICS INSTITUTE, INC. 1992-12-15 US claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US claimed
US-4364838-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1982-12-21 US claimed
EP-2511318-B1 METHOD FOR PRODUCING CONJUGATED POLYMER FUJIFILM CORP (JP) 2018-02-21 EP disclosed
US-9449732-B2 Charge transport film, method for producing the same, and light-emitting element and photoelectric conversion element using the same FUJIFILM CORPORATION (JP) 2016-09-20 US disclosed
EP-2511318-A1 METHOD FOR PRODUCING CONJUGATED POLYMER FUJIFILM Corporation (JP) 2012-10-17 EP disclosed
US-20120241326-A1 METHOD OF PREPARING CONJUGATED POLYMER FUJIFILM CORPORATION (JP) 2012-09-27 US disclosed
US-4473487-A 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-09-25 US disclosed
US-4364838-A Liquid crystal mixtures HOFFMANN-LA ROCHE INC. (US) 1982-12-21 US disclosed
US-4335012-A LIQUID CRYSTALS TIMEX CORPORATION (US) 1982-06-15 US disclosed
US-4322354-A 5-Substituted-2-(4-cyanophenyl)-1,3,-dioxanes TIMEX CORPORATION (US) 1982-03-30 US disclosed