Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362814 | 1.00 | GRM2 (0.48) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL8975343 | 1.00 | GRM2 (0.48) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL9719633 | 1.00 | GRM2 (0.48) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL5348257 | 1.00 | GRM2 (0.48) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL11290099 | 1.00 | GRM2 (0.48) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL10865557 | 1.00 | GRM2 (0.48) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL1934965 | 0.99 | GRM2 (0.46) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL4650784 | 0.99 | GRM2 (0.46) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL12695240 | 0.96 | TSHR (0.49) | GRM2TSHRHSD17B10ALDH1A1MGLL | |
| SCHEMBL9556130 | 0.95 | GRM2 (0.45) | GRM2TSHRHSD17B10ALDH1A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332392-B1 | Dioxane liquid crystal compounds | SHOWA SHELL SEKIYU (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5171471-A | Having wide range of phase transition temperatures for faster optical response times | SHOWA SHELL SEKIYU K.K. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0332392-A2 | Dioxane liquid crystal compounds | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1989-09-13 | — | — | EP | disclosed |