Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29950897 | 0.91 | AOC3 (0.39) | TP53ABCG2AOC3ALDH1A1NQO2 | |
| SCHEMBL1224244 | 0.91 | AOC3 (0.39) | TP53ABCG2AOC3ALDH1A1NQO2 | |
| SCHEMBL1224045 | 0.80 | ABCG2 (0.52) | NPC1RAB9ATP53SMN1; SMN2ABCG2 | |
| SCHEMBL30521296 | 0.80 | ABCG2 (0.52) | NPC1RAB9ATP53SMN1; SMN2ABCG2 | |
| SCHEMBL2032971 | 0.77 | P4HB (0.36) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL962423 | 0.77 | ABCG2 (0.44) | ABCG2PKMALDH1A1MAOBMAPK1 | |
| SCHEMBL29670249 | 0.77 | ABCG2 (0.44) | ABCG2PKMALDH1A1MAOBMAPK1 | |
| SCHEMBL4650783 | 0.73 | — | — | |
| SCHEMBL19492639 | 0.71 | NQO2 (0.47) | NPC1RAB9ATP53ABCG2AOC3 | |
| SCHEMBL8798169 | 0.70 | AOC3 (0.41) | NPC1RAB9ATP53ABCG2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971579-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007082076-A1 | 2-(POLY-SUBSTITUTED ARYL)-6-AMINO-5-HALO-4-PYRIMIDINECARBOXYLIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2007-07-19 | — | — | WO | disclosed |