Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 9/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.37 |
| ▸ | NPY2R | P49146 | 3/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593414 | 0.97 | NPY1R (0.42) | NPY1RCNR1CNR2NPY4RNPY5R | |
| SCHEMBL8126197 | 0.94 | NPY1R (0.43) | NPY1RCNR1CNR2NPY4RNPY5R | |
| SCHEMBL7753050 | 0.94 | NPY1R (0.43) | NPY1RCNR1CNR2NPY4RNPY5R | |
| SCHEMBL9195693 | 0.91 | NPY1R (0.42) | NPY1RCNR1CNR2NPY4RNPY5R | |
| SCHEMBL1389118 | 0.91 | CNR1 (0.41) | CNR1CNR2 | |
| SCHEMBL30905434 | 0.91 | CNR1 (0.41) | CNR1CNR2 | |
| SCHEMBL4651831 | 0.90 | CNR1 (0.42) | NPY1RCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL8120910 | 0.89 | CNR1 (0.41) | NPY1RCNR1CNR2 | |
| SCHEMBL1388356 | 0.89 | TDP1 (0.37) | NPY1RCNR1CNR2 | |
| SCHEMBL8119315 | 0.89 | NPY1R (0.42) | NPY1RCNR1CNR2NPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093803-B1 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI AVENTIS (FR) | 2008-09-17 | — | — | EP | disclosed |
| EP-0838217-B1 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI SYNTHELABO (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6313128-B1 | CAN BE USED AS LYPOLYSIS/LYPOGENESIS REGULATORS IN THE SKIN WITHOUT, INTERFERRING WITH THE SKIN'S NATURAL FUNCTIONS; FOR THERAPY OF SABORRHEA AND ACNE | SANOFI-SYNTHELABO (FR) | 2001-11-06 | — | — | US | disclosed |
| EP-1132463-A2 | Cosmetic composition comprising an antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-09-12 | — | — | EP | disclosed |
| EP-1093803-A2 | Cosmetic composition comprising antagonist of the neuropeptide Y receptor | SANOFI-SYNTHELABO (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-0838217-A2 | Cosmetic composition containing neuropeptide Y receptor antagonist | SANOFI (FR) | 1998-04-29 | — | — | EP | disclosed |