Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.39 |
| ▸ | NPY4R | P50391 | 6/20 | 0.37 |
| ▸ | NPY2R | P49146 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593414 | 0.94 | NPY1R (0.42) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL9200838 | 0.93 | CNR1 (0.42) | NPY1RCNR1CNR2TDP1 | |
| SCHEMBL4650863 | 0.91 | NPY1R (0.40) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL8126197 | 0.91 | NPY1R (0.43) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL7753050 | 0.91 | NPY1R (0.43) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL9196217 | 0.91 | MEN1 (0.42) | CNR1CNR2TDP1 | |
| SCHEMBL9201122 | 0.91 | TDP1 (0.48) | CNR1TDP1 | |
| SCHEMBL9199526 | 0.91 | CNR1 (0.43) | NPY1RCNR1CNR2NPY5RNPY2R | |
| SCHEMBL8127029 | 0.90 | NPY1R (0.41) | NPY1RCNR1CNR2NPY5RNPFFR1 | |
| SCHEMBL9201137 | 0.90 | NPY1R (0.42) | NPY1RCNR1CNR2NPY5RNPFFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |