SCHEMBL4650966

SCHEMBL4650966

CCCCS(=O)(=O)Nc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.66
HPGD P15428 3/20 0.58
LMNA P02545 2/20 0.58
AURKA O14965 1/20 0.54
KDR P35968 1/20 0.54
AURKB Q96GD4 1/20 0.54
BRD4 O60885 2/20 0.52
KEAP1 Q14145 1/20 0.50
KDM4E B2RXH2 1/20 0.49
ALDH1A1 P00352 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
NR3C2 P08235 1/20 0.49
THRA P10827 1/20 0.48
PGAM1 P18669 1/20 0.47
PSEN1 P49768 1/20 0.45
PSEN2 P49810 1/20 0.45
APH1B Q8WW43 1/20 0.45
NCSTN Q92542 1/20 0.45
APH1A Q96BI3 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL251932 0.94 AR (0.60) ARHPGDLMNAAURKAKDR
SCHEMBL11210096 0.93 AR (0.58) ARHPGDLMNAAURKAKDR
SCHEMBL14390532 0.93 AR (0.58) ARHPGDLMNAAURKAKDR
SCHEMBL28989097 0.89 AR (0.56) ARHPGDLMNAAURKAKDR
SCHEMBL255294 0.88 KEAP1 (0.54) ARHPGDLMNAAURKAKDR
SCHEMBL12789656 0.88 KEAP1 (0.52) ARHPGDLMNAKEAP1ALDH1A1
SCHEMBL9478842 0.87 AR (0.57) ARHPGDLMNAAURKAKDR
Hydrochloric Acid SCHEMBL31111910 0.86 KEAP1 (0.52) ARHPGDLMNAAURKAKDR
SCHEMBL11709119 0.84 HPGD (0.75) ARHPGDLMNAAURKAKDR
SCHEMBL6533144 0.83 CA1 (0.56) ARHPGDLMNAKEAP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5028347-A Polyamide Resins; Permanent Magnets For Electronic Equipment TONG YANG NYLON CO. LTD. (KR) 1991-07-02 US claimed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
CN-117858881-A Phospholipid compounds and methods of making and using the same 吉利德科学公司 2024-04-09 CN disclosed
CN-117835820-A Novel pesticide composition 希特逊库玛·阿尼凯特·多希 2024-04-05 CN disclosed
CN-112119075-B Condensed ring compound 豪夫迈·罗氏有限公司 2024-03-12 CN disclosed
CN-116963722-A Micelle nanoparticle and use thereof 生物欧赛加有限责任公司 2023-10-27 CN disclosed
CN-116648245-A Tetrahydroquinoline derivative and medical application thereof 东丽株式会社 2023-08-25 CN disclosed
CN-116457034-A Nanomaterial and method of use thereof 康涅狄格大学 2023-07-18 CN disclosed
CN-116322759-A Phospholipid compounds and uses thereof 吉利德科学公司 2023-06-23 CN disclosed
EP-3328843-B1 1,3,4-OXADIAZOLE SULFONAMIDE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP (KR) 2022-10-26 EP disclosed
EP-1470910-A1 Multi-layer hose Asahi Glass Co., Ltd. (JP) 2004-10-27 EP disclosed
CN-1534228-A Multi-layer hose 旭硝子株式会社 2004-10-06 CN disclosed
US-20040191440-A1 A multi-layer hose having a multi-layer structure containing an inner layer made of a fluorocopolymer and an outer layer made of polyamide resin ASAHI GLASS COMPANY LIMITED (JP) 2004-09-30 US disclosed
US-6656553-B2 Comprises ethylene-tetrafluoroethylene copolymer adhesive laminated to a polyamide resin; excellent interlaminar adhesive strength, antistatic properties, and fuel permeation-preventing properties; coextrusion molding ASAHI GLASS COMPANY, LIMITED (JP) 2003-12-02 US disclosed
US-20030035914-A1 Hose for fuel ASAHI GLASS COMPANY LIMITED (JP) 2003-02-20 US disclosed
EP-1276604-A1 HOSE FOR FUEL Asahi Glass Company, Limited (JP) 2003-01-22 EP disclosed
US-6410749-B1 REACTING A CARBONYL COMPOUND WITH ORGANOMETALLIC COMPOUND NIPPON SODA CO., LTD. (JP) 2002-06-25 US disclosed
WO-2001081077-A1 HOSE FOR FUEL ASAHI GLASS COMPANY, LIMITED (JP) 2001-11-01 WO disclosed
EP-1146037-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO., LTD. (JP) 2001-10-17 EP disclosed
US-5028347-A Polyamide Resins; Permanent Magnets For Electronic Equipment TONG YANG NYLON CO. LTD. (KR) 1991-07-02 US disclosed