SCHEMBL4650974

SCHEMBL4650974

CCCc1ccc(C(=O)Oc2ccc(C#N)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.54
THRB P10828 3/20 0.54
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
F2 P00734 1/20 0.51
ALDH1A1 P00352 2/20 0.50
MGLL Q99685 2/20 0.50
PLA2G1B P04054 1/20 0.50
KMT2A Q03164 1/20 0.50
ATG4B Q9Y4P1 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2D6 P10635 1/20 0.50
HIF1A Q16665 1/20 0.50
PRSS1 P07477 2/20 0.48
ACR P10323 2/20 0.48
NPC1 O15118 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9758798 1.00 MAPT (0.54) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL11742330 1.00 MAPT (0.54) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL8903841 0.96 MAPT (0.51) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL11340451 0.96 MAPT (0.57) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL9853916 0.92 MGLL (0.54) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL3088004 0.92 MGLL (0.54) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL11696699 0.92 MGLL (0.54) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL9407102 0.91 TSHR (0.57) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL8375386 0.91 TSHR (0.57) MAPTTHRBRAB9ASMN1; SMN2F2
SCHEMBL9853910 0.91 TSHR (0.57) MAPTTHRBRAB9ASMN1; SMN2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN claimed
EP-1599562-B9 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2008-09-24 EP claimed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US claimed
CN-100365096-C Nematic liquid crystal mixtures for bistable display devices NEMOPTIC (FR) 2008-01-30 CN claimed
EP-1599562-B1 NEMATIC LIQUID CRYSTAL MIXTURES FOR BISTABLE DISPLAY DEVICES NEMOPTIC (FR) 2007-05-16 EP claimed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US claimed
CN-1753969-A Nematic liquid crystal mixtures for bistable display devices NEMOPTIC (FR) 2006-03-29 CN claimed
US-20040188654-A1 Nematic liquid crystal mixtures for bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2004-09-30 US claimed
US-RE37270-E1 EXCELLENT ELECTRO-OPTIC STEEPNESS AND VIEWING ANGLE COMBINED WITH BIREFRINGENCE FOR USE IN STANDARD DISPLAY CELLS; MIXTURE OF 4-CYANO-3-FLUOROPHENYL BENZOATES, BENZONITRILES, ALKYLPHENYL ESTERS OF CYCLOHEXANE OR PHENYLCARBOXYLIC ACIDS MERCK PATENT GESELLSCHAFT (DE) 2001-07-10 US claimed
EP-0285617-B1 LIQUID CRYSTAL PHASE MERCK PATENT GmbH (DE) 1991-12-27 EP claimed
US-4886621-A ACCEPTABLE COMBINATION OF THRESHOLD STEEPNESS, VIEWING ANGLE AND TEMPERATURE DEPENDENCE AT LOW THRESHOLD VOLTAGE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-12-12 US claimed
JP-10112333-A None JP disclosed
US-12258509-B2 Optical component MERCK PATENT GMBH (DE) 2025-03-25 US disclosed
EP-4179040-B1 OPTICAL COMPONENT MERCK PATENT GMBH (DE) 2025-01-29 EP disclosed
CN-119264206-A Method for ring-opening fluorination of steroid epoxide 成都倍特药业股份有限公司 2025-01-07 CN disclosed
WO-1988002018-A1 LIQUID CRYSTAL PHASE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-03-24 WO disclosed
US-4639328-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-01-27 US disclosed
US-4620938-A Hydroterphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-11-04 US disclosed
US-4473487-A 4-Fluorobiphenyl derivatives, their preparation, and dielectrics and electro-optical display element containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-09-25 US disclosed
US-4208106-A FLUORESCENT DYE, LIQUID CRYSTAL BECKMAN INSTRUMENTS, INC. (US) 1980-06-17 US disclosed