Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dodecanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 4/20 | 0.50 |
| ▸ | CES1 | P23141 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL10454074 | 1.00 | FABP3 (0.56) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL18076263 | 0.96 | FABP3 (0.56) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL28305504 | 0.96 | FABP3 (0.56) | FABP3CA1CES2CES1NFKB1 | |
| Myristic Acid SCHEMBL9245302 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL35315 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Heptanoate SCHEMBL8361326 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Palmitic Acid SCHEMBL2452648 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL4869587 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Nonanoate SCHEMBL8365974 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL900922 | 0.96 | FABP3 (0.60) | FABP3CA1CES2CES1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1969029-A2 | CROSSLINKED POLY(ARYLENE ETHER), METHOD FOR PREPARING THEM, AND ARTICLE COMPRISING THEM | GENERAL ELECTRIC COMPANY (US) | 2008-09-17 | — | — | EP | claimed |
| WO-2007055948-A2 | CROSSLINKED POLY(ARYLENE ETHER), METHOD FOR PREPARING THEM, AND ARTICLE COMPRISING THEM | GENERAL ELECTRIC COMPANY (US) | 2007-05-18 | — | — | WO | claimed |
| US-20070106050-A1 | Crosslinked poly(arylene ether) composition, method, and article | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-05-10 | — | — | US | claimed |
| US-5948853-A | CONTAINING A ETHYLTRIACETOXYSILANE CROSSLINKER | GENERAL ELECTRIC COMPANY (US) | 1999-09-07 | — | — | US | claimed |
| US-5932650-A | IRON CARBOXYLATE | GENERAL ELECTRIC COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| JP-9310022-A | — | — | None | — | — | JP | disclosed |
| EP-1969029-A2 | CROSSLINKED POLY(ARYLENE ETHER), METHOD FOR PREPARING THEM, AND ARTICLE COMPRISING THEM | GENERAL ELECTRIC COMPANY (US) | 2008-09-17 | — | — | EP | disclosed |
| WO-2007055948-A2 | CROSSLINKED POLY(ARYLENE ETHER), METHOD FOR PREPARING THEM, AND ARTICLE COMPRISING THEM | GENERAL ELECTRIC COMPANY (US) | 2007-05-18 | — | — | WO | disclosed |
| US-20070106050-A1 | Crosslinked poly(arylene ether) composition, method, and article | CITIBANK, N.A., AS COLLATERAL AGENT | 2007-05-10 | — | — | US | disclosed |
| EP-0905210-B1 | Printable paper release compositions | GEN ELECTRIC (US) | 2004-03-10 | — | — | EP | disclosed |
| EP-0735086-B1 | 1-Component alkoxy curing RTV silicone sealant compositions | GEN ELECTRIC (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6077611-A | BLEND OF SILICONE AND POLYURETHANE | GENERAL ELECTRIC COMPANY (US) | 2000-06-20 | — | — | US | disclosed |
| US-5948853-A | CONTAINING A ETHYLTRIACETOXYSILANE CROSSLINKER | GENERAL ELECTRIC COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| US-5932650-A | IRON CARBOXYLATE | GENERAL ELECTRIC COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0905210-A1 | Printable paper release compositions | GENERAL ELECTRIC COMPANY (US) | 1999-03-31 | — | — | EP | disclosed |
| JP-H09310022-A | ONE-PACK TYPE ROOM TEMPERATURE VULCANIZABLE SILICONE SEALANT IMPROVED IN POT LIFE | GENERAL ELECTRIC CO <GE> | 1997-12-02 | — | — | JP | disclosed |
| EP-0735086-A2 | 1-Component alkoxy curing RTV silicone sealant compositions | GENERAL ELECTRIC COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5519104-A | DIALKYLTIN DIALKANOATE CURING CATALYST | GENERAL ELECTRIC COMPANY (US) | 1996-05-21 | — | — | US | disclosed |