SCHEMBL4651973

SCHEMBL4651973

CCCCC(CNS(=O)(=O)c1ccccc1)Cc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
TSHR P16473 1/20 0.48
KEAP1 Q14145 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
GBA1 P04062 1/20 0.46
TP53 P04637 2/20 0.44
MAPT P10636 2/20 0.44
PKM P14618 2/20 0.44
KDM4E B2RXH2 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.42
CYP3A4 P08684 1/20 0.42
ATM Q13315 1/20 0.42
CA9 Q16790 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226294 0.87 ALDH1A1 (0.51) ALDH1A1TSHRKEAP1SMN1; SMN2GBA1
SCHEMBL15562699 0.77 CSNK1E (0.50) ALDH1A1KDM4ECYP1A2
SCHEMBL7147691 0.77 CSNK1E (0.50) ALDH1A1KDM4E
SCHEMBL29675410 0.74 ALDH1A1 (0.52) ALDH1A1TSHRKDM4EKMT2ACYP3A4
SCHEMBL3469704 0.74 GBA1 (0.55) ALDH1A1TSHRGBA1MAPTLMNA
SCHEMBL15562664 0.73 CSNK1E (0.47) ALDH1A1KDM4ECYP1A2
SCHEMBL3466390 0.73 ALDH1A1 (0.49) ALDH1A1TSHRKDM4ECYP3A4
SCHEMBL10613932 0.73 ALDH1A1 (0.45) ALDH1A1TSHRSMN1; SMN2GBA1MAPT
SCHEMBL11136790 0.73 CA12 (0.56) ALDH1A1TSHRGBA1CA12CYP3A4
SCHEMBL20893266 0.73 SMN1; SMN2 (0.61) ALDH1A1TSHRKEAP1SMN1; SMN2GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1470910-B1 Multi-layer hose ASAHI GLASS CO LTD (JP) 2008-09-17 EP disclosed
US-6855787-B2 A multi-layer hose having a multi-layer structure containing an inner layer made of a fluorocopolymer and an outer layer made of polyamide resin ASAHI GLASS COMPANY, LIMITED (JP) 2005-02-15 US disclosed
EP-1470910-A1 Multi-layer hose Asahi Glass Co., Ltd. (JP) 2004-10-27 EP disclosed
US-20040191440-A1 A multi-layer hose having a multi-layer structure containing an inner layer made of a fluorocopolymer and an outer layer made of polyamide resin ASAHI GLASS COMPANY LIMITED (JP) 2004-09-30 US disclosed