Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | AGXT | P21549 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652279 | 1.00 | SLC1A3 (0.36) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL1774783 | 0.83 | TACR1 (0.39) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL1774437 | 0.83 | TACR1 (0.39) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL19928526 | 0.82 | MAPT (0.36) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL14747384 | 0.81 | MAPT (0.35) | IDO1AGXTBTN3A1MAPT | |
| SCHEMBL15892778 | 0.80 | MAPT (0.37) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL15892776 | 0.78 | MAPT (0.33) | CYP2C19BTN3A1MAPTTSHR | |
| SCHEMBL21727813 | 0.78 | MAPT (0.36) | SLC1A3SLC1A2SLC1A1CYP2D6MEN1 | |
| SCHEMBL1775195 | 0.77 | TACR1 (0.47) | SLC1A1IDO1AGXTTACR1TSHR | |
| SCHEMBL18591520 | 0.77 | MAPT (0.35) | CYP2C19BTN3A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831226-A4 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1831226-A2 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006074003-A2 | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-07-13 | — | — | WO | disclosed |