Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15892776 | 0.94 | MAPT (0.33) | MAPTBTN3A1CA1 | |
| SCHEMBL19928526 | 0.88 | MAPT (0.36) | MAPTBTN3A1IDO1AGXTBACE1 | |
| SCHEMBL21727813 | 0.86 | MAPT (0.36) | MAPTBTN3A1BACE1CA1 | |
| SCHEMBL15892778 | 0.86 | MAPT (0.37) | MAPTBTN3A1IDO1BACE1CA1 | |
| SCHEMBL19928558 | 0.83 | MAPT (0.35) | MAPTBTN3A1BACE1CA1 | |
| SCHEMBL9304192 | 0.83 | BTN3A1 (0.33) | MAPTBTN3A1BACE1 | |
| SCHEMBL18591520 | 0.83 | MAPT (0.35) | MAPTBTN3A1BACE1CA1 | |
| SCHEMBL14747381 | 0.83 | CA1 (0.41) | MAPTCA1 | |
| SCHEMBL4652159 | 0.81 | SLC1A3 (0.36) | MAPTBTN3A1IDO1AGXT | |
| SCHEMBL4652279 | 0.81 | SLC1A3 (0.36) | MAPTBTN3A1IDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |