SCHEMBL4652807

SCHEMBL4652807

CC(C)[C@H](N)C(=O)NCC(=O)Oc1ccccc1C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ POLB P06746 2/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ PPARG P37231 1/20 0.40
▸ SSTR4 P31391 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ ATM Q13315 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ RXRA P19793 1/20 0.38
▸ RXRB P28702 1/20 0.38
▸ RXRG P48443 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ LMNA P02545 2/20 0.37
▸ EPHX2 P34913 1/20 0.36
▸ CTSC P53634 1/20 0.36
▸ MRGPRX4 Q96LA9 1/20 0.36
▸ NOTUM Q6P988 1/20 0.36
▸ CARM1 Q86X55 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28110893 0.80 SLC1A3 (0.42) SMN1; SMN2ALDH1A1ATML3MBTL1
SCHEMBL27475534 0.79 PPARG (0.44) HPGDSMN1; SMN2POLBMAPK1PPARG
SCHEMBL28111448 0.78 KIF11 (0.44) SMN1; SMN2ALDH1A1KMT2ALMNA
SCHEMBL15763932 0.77 PPARG (0.53) HPGDSMN1; SMN2POLBMAPK1PPARG
SCHEMBL938151 0.76 PPARG (0.40) HPGDSMN1; SMN2PPARGALDH1A1ATM
SCHEMBL4418520 0.75 PPARG (0.44) HPGDSMN1; SMN2POLBMAPK1PPARG
SCHEMBL6584647 0.74 PPARG (0.50) HPGDSMN1; SMN2POLBMAPK1PPARG
SCHEMBL2002076 0.74 PPARG (0.50) HPGDSMN1; SMN2POLBMAPK1PPARG
SCHEMBL15454362 0.73 HPGD (0.54) HPGDSMN1; SMN2POLBMAPK1PPARG
SCHEMBL15763991 0.72 MEN1 (0.51) HPGDSMN1; SMN2POLBMAPK1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4440531-B1 KIT AND METHOD FOR TREATING SKIN OREAL (FR) 2026-01-21 — — EP claimed
EP-4440531-A1 KIT AND METHOD FOR TREATING SKIN L'OREAL (FR) 2024-10-09 — — EP claimed
WO-2023101902-A1 KIT AND METHOD FOR TREATING SKIN L'OREAL (FR) 2023-06-08 — — WO claimed
US-20230165777-A1 KIT AND METHOD FOR TREATING SKIN L'OREAL (FR) 2023-06-01 — — US claimed
EP-1415644-B1 Cosmetic process for smoothing out expression wrinkles by topical application of a perfume composition OREAL (FR) 2008-02-20 — — EP claimed
EP-4440531-B1 KIT AND METHOD FOR TREATING SKIN OREAL (FR) 2026-01-21 — — EP disclosed
EP-4440531-A1 KIT AND METHOD FOR TREATING SKIN L'OREAL (FR) 2024-10-09 — — EP disclosed
WO-2023101902-A1 KIT AND METHOD FOR TREATING SKIN L'OREAL (FR) 2023-06-08 — — WO disclosed
US-20230165777-A1 KIT AND METHOD FOR TREATING SKIN L'OREAL (FR) 2023-06-01 — — US disclosed
US-20230133445-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF SKIN L'OREAL (FR) 2023-05-04 — — US disclosed
EP-3840724-A1 COSMETIC COMPOSITIONS COMPRISING ACETYL TRIFLUOROMETHYLPHENYL VALYLGLYCINE L'OREAL (FR) 2021-06-30 — — EP disclosed
EP-3840724-A1 COSMETIC COMPOSITIONS COMPRISING ACETYL TRIFLUOROMETHYLPHENYL VALYLGLYCINE L'OREAL (FR) 2021-06-30 — — EP disclosed
WO-2020041389-A1 COSMETIC COMPOSITIONS COMPRISING ACETYL TRIFLUOROMETHYLPHENYL VALYLGLYCINE L'OREAL (FR) 2020-02-27 — — WO disclosed
WO-2020041389-A1 COSMETIC COMPOSITIONS COMPRISING ACETYL TRIFLUOROMETHYLPHENYL VALYLGLYCINE L'OREAL (FR) 2020-02-27 — — WO disclosed
US-10449133-B1 Cosmetic compositions comprising acetyl trifluoromethylphenyl valylglycine L'OREAL (FR) 2019-10-22 — — US disclosed
EP-3551161-A1 NON-STICKY STABLE COMPOSITION L'Oréal (FR) 2019-10-16 — — EP disclosed
WO-2018105503-A1 NON-STICKY STABLE COMPOSITION L'OREAL (FR) 2018-06-14 — — WO disclosed
EP-2717970-A2 POLYETHYLENE GLYCOL-FREE COSMETIC OR DERMATOLOGICAL PREPARATIONS Beiersdorf AG (DE) 2014-04-16 — — EP disclosed
WO-2012167906-A2 COSMETIC OR DERMATOLOGICAL PREPARATIONS WITH IMPROVED RHEOLOGICAL PROPERTIES BEIERSDORF AG (DE) 2012-12-13 — — WO disclosed
WO-2012167905-A2 POLYETHYLENE GLYCOL-FREE COSMETIC OR DERMATOLOGICAL PREPARATIONS BEIERSDORF AG (DE) 2012-12-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10449133-B1 Cosmetic compositions comprising acetyl trifluoromethylphenyl valylglycine SUCLG1, ACACB, VCL HPGD 1098/4885SMN1; SMN2 4401/4885POLB 551/4885
US-20230165777-A1 KIT AND METHOD FOR TREATING SKIN KIT, GK, GANC HPGD 2411/4885SMN1; SMN2 3081/4885POLB 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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