SCHEMBL4653115

SCHEMBL4653115

CCCCC(=COC(=O)/C=C/C(=O)OC=C(CC)CCCC)CC

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.44
HCAR2 Q8TDS4 5/20 0.39
CES1 P23141 3/20 0.38
CES2 O00748 2/20 0.38
ALDH1A1 P00352 3/20 0.35
TP53 P04637 1/20 0.35
CA1 P00915 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
POLA1 P09884 1/20 0.33
TRPA1 O75762 1/20 0.32
AKR1B1 P15121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8625179 1.00 ATM (0.44) ATMHCAR2CES1CES2ALDH1A1
SCHEMBL4651896 1.00 ATM (0.44) ATMHCAR2CES1CES2ALDH1A1
SCHEMBL4653114 1.00 ATM (0.44) ATMHCAR2CES1CES2ALDH1A1
SCHEMBL4651898 1.00 ATM (0.44) ATMHCAR2CES1CES2ALDH1A1
SCHEMBL4651904 1.00 ATM (0.44) ATMHCAR2CES1CES2ALDH1A1
Fumaric Acid SCHEMBL8812478 0.87 HCAR2 (0.50) ATMHCAR2ALDH1A1MAPTRAB9A
Maleic Acid SCHEMBL8808782 0.87 HCAR2 (0.50) ATMHCAR2ALDH1A1MAPTRAB9A
SCHEMBL4521307 0.85 TSHR (0.47) ATMCES1CES2ALDH1A1TP53
SCHEMBL11237871 0.82 CES1 (0.40) ATMCES1CES2ALDH1A1TP53
SCHEMBL11237872 0.82 CES1 (0.40) ATMCES1CES2ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0847380-B1 MIXTURE OF ESTERS AND USE THEREOF BP CHEM INT LTD (GB) 2001-08-16 EP claimed
US-6130275-A AS REACTIVE DILUENT INA PAINT OR COATING FORMULATION BP CHEMICALS LIMITED (GB) 2000-10-10 US claimed
WO-1997002229-A1 REACTIVE DILUENTS BP CHEMICALS LIMITED (GB) 1997-01-23 WO claimed
EP-1608694-B1 PROCESS FOR THE PREPARATION OF HIGH SOLIDS URETHANE ALKYDS PPG BV (NL) 2008-11-05 EP disclosed
EP-1608694-A1 PROCESS FOR THE PREPARATION OF HIGH SOLIDS URETHANE ALKYDS SigmaKalon B.V. (NL) 2005-12-28 EP disclosed
WO-2004101639-A1 PROCESS FOR THE PREPARATION OF HIGH SOLIDS URETHANE ALKYDS SIGMAKALON B.V. (NL) 2004-11-25 WO disclosed
EP-0847380-B1 MIXTURE OF ESTERS AND USE THEREOF BP CHEM INT LTD (GB) 2001-08-16 EP disclosed
US-6130275-A AS REACTIVE DILUENT INA PAINT OR COATING FORMULATION BP CHEMICALS LIMITED (GB) 2000-10-10 US disclosed
WO-1997002229-A1 REACTIVE DILUENTS BP CHEMICALS LIMITED (GB) 1997-01-23 WO disclosed