Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.40 |
| ▸ | CES2 | O00748 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237871 | 1.00 | CES1 (0.40) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL27320545 | 0.92 | CES2 (0.43) | CES1CES2ALDH1A1DGKAGPR84 | |
| SCHEMBL28682792 | 0.84 | CES2 (0.46) | CES1CES2ALDH1A1DGKAGPR84 | |
| SCHEMBL8629856 | 0.84 | CES1 (0.39) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL8629859 | 0.84 | CES1 (0.39) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL2801039 | 0.83 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8625179 | 0.82 | ATM (0.44) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL4651904 | 0.82 | ATM (0.44) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL4651898 | 0.82 | ATM (0.44) | CES1CES2ALDH1A1TP53CA1 | |
| SCHEMBL4651896 | 0.82 | ATM (0.44) | CES1CES2ALDH1A1TP53CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326070-A | ESTERS, OXIDATION RESISTANT LUBRICANTS | EMERY INDUSTRIES, INC. (US) | 1982-04-20 | — | — | US | disclosed |