Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5688611 | 0.89 | KCNH2 (0.40) | KCNH2LMNAALDH1A1TSHRCES2 | |
| SCHEMBL28841075 | 0.80 | KCNH2 (0.43) | KCNH2LMNAALDH1A1CES2CES1 | |
| SCHEMBL5433591 | 0.75 | KCNH2 (0.41) | KCNH2LMNAALDH1A1TSHRCES2 | |
| SCHEMBL4748758 | 0.72 | NPC1 (0.38) | LMNAALDH1A1KMT2AHTT | |
| SCHEMBL1906654 | 0.70 | KCNH2 (0.38) | KCNH2LMNAALDH1A1TSHRCES2 | |
| SCHEMBL30622138 | 0.70 | NPC1 (0.37) | LMNAALDH1A1TSHRCES1KMT2A | |
| SCHEMBL11333120 | 0.70 | TSHR (0.40) | KCNH2LMNAALDH1A1TSHRCES2 | |
| SCHEMBL15353512 | 0.70 | TSHR (0.40) | KCNH2LMNAALDH1A1TSHRCES2 | |
| SCHEMBL14957998 | 0.69 | TSHR (0.37) | LMNAALDH1A1TSHRCES2CES1 | |
| SCHEMBL5433594 | 0.69 | TSHR (0.37) | LMNAALDH1A1TSHRCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505412-B1 | Plastic lens and process for producing the lens | HOYA CORP (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1505412-A1 | Plastic lens and process for producing the lens | HOYA CORPORATION (JP) | 2005-02-09 | — | — | EP | disclosed |