SCHEMBL5433591

SCHEMBL5433591

CCCCCCCCCCCCOC1(O)C=CC(C(=O)c2ccccc2)C=C1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.41
TSHR P16473 3/20 0.40
LMNA P02545 3/20 0.40
CES2 O00748 2/20 0.40
CES1 P23141 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 2/20 0.40
NAAA Q02083 1/20 0.40
PPARG P37231 3/20 0.39
PLA2G4B P0C869 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1906654 0.82 KCNH2 (0.38) KCNH2TSHRLMNACES2CES1
SCHEMBL6688022 0.81 GSK3B (0.35) LMNACES2CES1ALDH1A1KDM4E
SCHEMBL21224652 0.79 PPARG (0.42) TSHRLMNAALDH1A1TP53PPARG
SCHEMBL10449056 0.79 PPARG (0.42) TSHRLMNAALDH1A1TP53PPARG
SCHEMBL5137770 0.77 CES2 (0.41) KCNH2TSHRLMNACES2CES1
SCHEMBL3643052 0.76 TSHR (0.40) TSHRLMNACES2CES1ALDH1A1
SCHEMBL4653151 0.75 KCNH2 (0.40) KCNH2TSHRLMNACES2CES1
SCHEMBL5688611 0.75 KCNH2 (0.40) KCNH2TSHRLMNACES2CES1
SCHEMBL10583152 0.75 GAA (0.39) KCNH2LMNACES2CES1ALDH1A1
SCHEMBL5677227 0.71 CES2 (0.41) TSHRCES2CES1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020193477-A1 Method for dispersing a hydrophobic additive in an aqueous media WALKER KENNETH RAYMOND (GB) 2002-12-19 US claimed
EP-1192207-A1 AQUEOUS APPLICATION OF ADDITIVES TO POLYMERIC PARTICLES EASTMAN CHEMICAL COMPANY (US) 2002-04-03 EP claimed
WO-2001000714-A1 AQUEOUS APPLICATION OF ADDITIVES TO POLYMERIC PARTICLES EASTMAN CHEMICAL COMPANY (US) 2001-01-04 WO claimed
JP-2986822-B2 1999-12-06 JP claimed
EP-0526546-B1 SOLID-FORM ADDITIVE SYSTEMS DISPERSIBLE IN AQUEOUS MEDIA EASTMAN CHEM CO (US) 1996-07-17 EP claimed
EP-0606344-B1 SOLID-FORM ADDITIVE SYSTEMS DISPERSIBLE IN AQUEOUS MEDIA AND METHOD FOR THEIR PREPARATION EASTMAN CHEM CO (US) 1996-01-03 EP claimed
US-5358560-A For treating, coating polymers; antioxidants, slip agents antistatics, stabilizers, blowing agents, fireproofing EASTMAN CHEMICAL COMPANY (US) 1994-10-25 US claimed
EP-0606344-A1 SOLID-FORM ADDITIVE SYSTEMS DISPERSIBLE IN AQUEOUS MEDIA AND METHOD FOR THEIR PREPARATION. EASTMAN KODAK CO (US) 1994-07-20 EP claimed
US-5300256-A Encapsulated EASTMAN CHEMICAL COMPANY (US) 1994-04-05 US claimed
US-5204022-A Heating, adding surfactant EASTMAN KODAK COMPANY (US) 1993-04-20 US claimed
US-5153029-A Mixing melted polymer additives with surfactants, then with water yields(after agitation) water in oil emulsion which is cooled to give encapsulated emulsion particles EASTMAN KODAK COMPANY (US) 1992-10-06 US claimed
EP-0486600-A1 SOLID-FORM ADDITIVE SYSTEMS DISPERSIBLE IN AQUEOUS MEDIA EASTMAN KODAK COMPANY (US) 1992-05-27 EP claimed
US-5096493-A Aqueous additive systems, methods and polymeric particles EASTMAN KODAK COMPANY (US) 1992-03-17 US claimed
EP-0438425-A1 AQUEOUS ADDITIVE SYSTEMS, METHODS AND POLYMERIC PARTICLES EASTMAN CHEMICAL COMPANY (US) 1991-07-31 EP claimed
US-5007961-A Aqueous additive systems, methods and polymeric particles EASTMAN KODAK COMPANY (US) 1991-04-16 US claimed
EP-0416022-A1 AQUEOUS ADDITIVE SYSTEMS, METHODS AND POLYMERIC PARTICLES EASTMAN KODAK COMPANY (US) 1991-03-13 EP claimed
WO-1991002020-A1 SOLID-FORM ADDITIVE SYSTEMS DISPERSIBLE IN AQUEOUS MEDIA EASTMAN KODAK COMPANY (US) 1991-02-21 WO claimed
EP-0413647-A2 Solid-form additive systems dispersible in aqueous media, methods for the preparation and application thereof to polymeric particles EASTMAN CHEMICAL COMPANY (US) 1991-02-20 EP claimed
WO-1990002770-A2 AQUEOUS ADDITIVE SYSTEMS, METHODS AND POLYMERIC PARTICLES EASTMAN KODAK COMPANY (US) 1990-03-22 WO claimed
WO-1989011502-A1 AQUEOUS ADDITIVE SYSTEMS, METHODS AND POLYMERIC PARTICLES EASTMAN KODAK COMPANY (US) 1989-11-30 WO claimed