Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774380 | 1.00 | MAPT (0.52) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL22774649 | 0.87 | BDKRB1 (0.38) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL22774647 | 0.87 | BDKRB1 (0.38) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL22734425 | 0.86 | MAPT (0.37) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL22734424 | 0.86 | MAPT (0.37) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30810261 | 0.86 | MAPT (0.37) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL6106517 | 0.83 | MAPT (0.55) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4654569 | 0.81 | MAPT (0.45) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL2512829 | 0.81 | MAPT (0.45) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL22774369 | 0.79 | MEN1 (0.44) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831226-A4 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1831226-A2 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006074003-A2 | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-07-13 | — | — | WO | disclosed |