Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6106517 | 0.91 | MAPT (0.55) | MAPTPOLBMEN1KMT2ACACNA2D1 | |
| SCHEMBL12020848 | 0.86 | CACNA2D1 (0.39) | MAPTPOLBMEN1KMT2ACACNA2D1 | |
| SCHEMBL2086455 | 0.83 | MAPT (0.43) | MAPTPOLBMEN1KMT2ACACNA2D1 | |
| SCHEMBL9386488 | 0.83 | MAPT (0.43) | MAPTPOLBMEN1KMT2ACACNA2D1 | |
| SCHEMBL22749325 | 0.82 | MAPT (0.37) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL22749326 | 0.82 | MAPT (0.37) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL29508404 | 0.82 | MAPT (0.37) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1774882 | 0.81 | MAPT (0.42) | MAPTPOLBMEN1KMT2ANPC1 | |
| SCHEMBL4653497 | 0.81 | MAPT (0.52) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL1774380 | 0.81 | MAPT (0.52) | MAPTPOLBMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831226-A4 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-11-05 | — | — | EP | disclosed |
| EP-1831226-A2 | CHIRAL FUSED 1,2 IMIDAZO 4,5-c RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006074003-A2 | CHIRAL FUSED [1,2]IMIDAZO[4,5-c] RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-07-13 | — | — | WO | disclosed |