SCHEMBL465352

SCHEMBL465352

CCCCc1cc(O)ccc1-c1ccc(O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.58
ESR1 P03372 12/20 0.50
ESR2 Q92731 4/20 0.50
TP53 P04637 2/20 0.50
CYP3A4 P08684 2/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
KMT2A Q03164 2/20 0.50
ALOX5 P09917 1/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.50
HTT P42858 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.44
ERAP1 Q9NZ08 1/20 0.44
ADRA2A P08913 2/20 0.43
ADORA3 P0DMS8 2/20 0.43
TACR2 P21452 2/20 0.43
SLC6A2 P23975 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3807373 0.98 TYR (0.56) TYRESR1ESR2TP53CYP3A4
SCHEMBL10438718 0.93 ALOX5 (0.60) TYRESR1ESR2TP53CYP3A4
SCHEMBL1765204 0.90 TYR (0.54) TYRESR1ESR2TP53CYP3A4
SCHEMBL786818 0.89 ESR1 (0.53) TYRESR1ESR2ALOX5HSD17B10
SCHEMBL1237905 0.89 TYR (0.66) TYRESR1ESR2TP53CYP3A4
SCHEMBL27999819 0.88 ESR1 (0.50) TYRESR1ESR2TP53CYP3A4
SCHEMBL3811351 0.87 ESR1 (0.51) TYRESR1ESR2ALOX5HSD17B10
SCHEMBL20407416 0.86 CYP3A4 (0.51) TYRESR1ESR2TP53CYP3A4
SCHEMBL19854385 0.85 TP53 (0.54) TYRESR1TP53CYP3A4MEN1
SCHEMBL19854457 0.85 TP53 (0.54) TYRESR1TP53CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985704-B1 Nitrile resin composition MITSUI CHEMICALS INC (JP) 2003-11-05 EP claimed
US-6084028-A TRANSPARENT ANTISTATIC POLYMERS HAVING MATRIX OF GRAFT POLYMERS CONTAINING UNSATURATED NITRILES, ESTERS, OLEFINS AND CONJUGATED DIENES BLENDED WITH CO- OR TERPOLYMERS OF AMIDES, ESTERS OR ETHERS, VISCOSITY RATIOS, REFRACTIVE INDICES MITSUI CHEMICALS, INC. (JP) 2000-07-04 US claimed
EP-0985704-A1 Nitrile resin composition Mitsui Chemicals, Inc. (JP) 2000-03-15 EP claimed
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US claimed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP claimed
US-4923955-A Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
US-12383009-B2 Fiber for artificial hair, and wig ADERANS COMPANY LIMITED (JP) 2025-08-12 US disclosed
WO-2022009445-A9 ANTISTATIC AGENT, ANTISTATIC RESIN COMPOSITION, AND MOLDED ARTICLE 三洋化成工業株式会社 2025-01-16 WO disclosed
EP-4159824-B1 ANTISTATIC AGENT, ANTISTATIC RESIN COMPOSITION, AND MOLDED PRODUCT SANYO CHEMICAL IND LTD (JP) 2025-01-01 EP disclosed
EP-4137625-B1 ANTISTATIC AGENT SANYO CHEMICAL IND LTD (JP) 2024-03-27 EP disclosed
US-20240057704-A1 FIBER FOR ARTIFICIAL HAIR, AND WIG ADERANS COMPANY LIMITED (JP) 2024-02-22 US disclosed
EP-4302624-A1 FIBER FOR ARTIFICIAL HAIR, AND WIG Aderans Company Limited (JP) 2024-01-10 EP disclosed
US-20230323001-A1 ANTISTATIC AGENT, ANTISTATIC RESIN COMPOSITION, AND MOLDED ARTICLE SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2023-10-12 US disclosed
EP-0700532-A1 ALIGNMENT LAYER FOR LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1996-03-13 EP disclosed
WO-1994028458-A1 ALIGNMENT LAYER FOR LIQUID CRYSTALS HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-08 WO disclosed
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US disclosed
EP-0383177-A2 Cross-linkable thermotropic liquid crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1990-08-22 EP disclosed
US-4923955-A Thermotropic liquid-crystalline aromatic polyesters of substituted 4,4'-dihydroxy-diphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US disclosed
EP-0321107-A1 Thermotropic liquid-crystalline aromatic polyesters HIMONT ITALIA S.r.l. (IT) 1989-06-21 EP disclosed
US-4357385-A BLEND OF POLYESTER WITH ETHYLENE TEREPHTHALATE UNITS AND POLYETHYLENE NAPHTHALENEDICARBOXYLATE TEIJIN LIMITED (JP) 1982-11-02 US disclosed