SCHEMBL4654233

SCHEMBL4654233

O=C(O)C(F)CCCCCCCCCOc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 7/20 0.54
HDAC2 Q92769 7/20 0.54
KCNA3 P22001 1/20 0.53
TDP1 Q9NUW8 1/20 0.49
HDAC3 O15379 4/20 0.49
HDAC4 P56524 4/20 0.49
HDAC7 Q8WUI4 4/20 0.49
HDAC10 Q969S8 4/20 0.49
HDAC11 Q96DB2 4/20 0.49
HDAC8 Q9BY41 4/20 0.49
HDAC6 Q9UBN7 4/20 0.49
HDAC9 Q9UKV0 4/20 0.49
HDAC5 Q9UQL6 4/20 0.49
MAPT P10636 1/20 0.49
PKM P14618 1/20 0.46
PPARG P37231 1/20 0.46
PPARA Q07869 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7507751 0.93 TDP1 (0.55) HDAC1HDAC2KCNA3TDP1PKM
SCHEMBL4756791 0.84 TDP1 (0.61) HDAC1HDAC2KCNA3TDP1HDAC3
SCHEMBL5508343 0.84 TDP1 (0.61) HDAC1HDAC2KCNA3TDP1HDAC3
SCHEMBL5514899 0.82 TDP1 (0.63) HDAC1HDAC2KCNA3TDP1HDAC3
SCHEMBL9774296 0.81 RARB (0.54) HDAC1HDAC2HDAC3HDAC4HDAC7
SCHEMBL10430063 0.80 KCNA3 (0.64) HDAC1HDAC2KCNA3HDAC3HDAC4
SCHEMBL10933261 0.79 KCNA3 (0.57) HDAC1HDAC2KCNA3TDP1HDAC3
SCHEMBL6053433 0.78 KCNA3 (0.67) HDAC1HDAC2KCNA3TDP1HDAC3
SCHEMBL6159560 0.78 KCNA3 (0.55) HDAC1HDAC2KCNA3TDP1PKM
SCHEMBL6161530 0.78 KCNA3 (0.55) HDAC1HDAC2KCNA3TDP1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1113033-B1 Polyhydroxyalkanoate CANON KK (JP) 2008-11-26 EP disclosed
EP-1118629-B1 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KK (JP) 2007-04-25 EP disclosed
EP-1188782-B1 Polyhydroxyalkanoate and manufacturing method thereof CANON KK (JP) 2007-04-04 EP disclosed
US-7169598-B2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2007-01-30 US disclosed
US-7078200-B2 Method for manufacturing a polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2006-07-18 US disclosed
US-7056708-B2 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KABUSHIKI KAISHA (JP) 2006-06-06 US disclosed
EP-1367078-B1 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KK (JP) 2006-04-19 EP disclosed
EP-1130043-B1 Polyhydroxyalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same CANON KK (JP) 2006-01-25 EP disclosed
US-6861550-B2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2005-03-01 US disclosed
US-20040092702-A1 Method for manufacturing a polyhydroxyalkanoate CANON KABUSHIKI KAISHA (JP) 2004-05-13 US disclosed
US-20020160467-A1 Polyhydroxyalkanoate and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2002-10-31 US disclosed
US-20020065389-A1 Polyhydroxyalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same CANON KABUSHIKI KAISHA (JP) 2002-05-30 US disclosed
EP-1188782-A2 Polyhydroxyalkanoate and manufacturing method thereof CANON KABUSHIKI KAISHA (JP) 2002-03-20 EP disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US disclosed
EP-1130043-A2 Polyhydroxylalkanoate containing 3-hydroxythienylalkanoic acid as monomer unit and method for producing the same CANON KABUSHIKI KAISHA (JP) 2001-09-05 EP disclosed
EP-1130042-A2 Polyhydroxyalkanoate containing 3-hydroxybenzoylalkanoic acid as monomer unit, and method for producing the same CANON KABUSHIKI KAISHA (JP) 2001-09-05 EP disclosed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed
JP-2000072865-A POLYESTER AND ITS PRODUCTION NAGOYA CITY 2000-03-07 JP disclosed