Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159560 | 1.00 | KCNA3 (0.55) | KCNA3ITGB3ITGA2BLTA4HTDP1 | |
| SCHEMBL5288095 | 0.95 | TDP1 (0.55) | KCNA3ITGB3ITGA2BLTA4HTDP1 | |
| Bromide SCHEMBL6049715 | 0.92 | LTA4H (0.56) | KCNA3ITGB3ITGA2BLTA4HTDP1 | |
| Bromide SCHEMBL6049719 | 0.92 | LTA4H (0.56) | KCNA3ITGB3ITGA2BLTA4HTDP1 | |
| SCHEMBL5082950 | 0.89 | LTA4H (0.53) | KCNA3ITGB3ITGA2BLTA4HTDP1 | |
| SCHEMBL5082944 | 0.89 | LTA4H (0.53) | KCNA3ITGB3ITGA2BLTA4HTDP1 | |
| SCHEMBL9090603 | 0.89 | LTA4H (0.53) | KCNA3ITGB3ITGA2BLTA4HTDP1 | |
| Bromide SCHEMBL6049690 | 0.89 | HDAC1 (0.55) | ITGB3ITGA2BLTA4HHDAC1HDAC2 | |
| Bromide SCHEMBL6049689 | 0.89 | HDAC1 (0.55) | ITGB3ITGA2BLTA4HHDAC1HDAC2 | |
| SCHEMBL4105743 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1504094-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | Pharmacia Corporation (US) | 2005-02-09 | — | — | EP | disclosed |
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | PHARMACIA CORPORATION | 2004-01-29 | — | — | US | disclosed |
| WO-2003095475-A2 | PEPTIDE COMPOUNDS AND THEIR USE AS PROTEASE SUBSTRATES | PHARMACIA CORPORATION (US) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040018561-A1 | Peptide compounds and their use as protease substrates | MMP3, MMP25, MMP11 | KCNA3 3431/4885ITGB3 4095/4885ITGA2B 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.