Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653191 | 0.90 | PPARA (0.61) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4654444 | 0.89 | PPARA (0.68) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4654281 | 0.88 | PPARA (0.71) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4654357 | 0.88 | PPARA (0.71) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4654500 | 0.88 | PPARA (0.71) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4654279 | 0.88 | PPARA (0.71) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4654508 | 0.88 | PPARA (0.71) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4655436 | 0.88 | PPARA (0.71) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL4653153 | 0.88 | PPARA (0.71) | HSP90AB1KDM4EPPARAESR1SHBG | |
| SCHEMBL5709868 | 0.87 | KMT2A (0.59) | HSP90AB1KDM4EESR1SHBGESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2746822-B1 | PLASTIC LENS | HOYA CORP (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-8895661-B2 | Plastic lens | HOYA CORPORATION (JP) | 2014-11-25 | — | — | US | disclosed |
| EP-2746822-A1 | PLASTIC LENS | HOYA CORPORATION (JP) | 2014-06-25 | — | — | EP | disclosed |
| EP-1505412-B1 | Plastic lens and process for producing the lens | HOYA CORP (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20070141355-A1 | Plastic lens and process for preparing the lens | HOYA CORPORATION | 2007-06-21 | — | — | US | disclosed |
| US-20050046967-A1 | Plastic lens and process for preparing the lens | HOYA CORPORATION (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1505412-A1 | Plastic lens and process for producing the lens | HOYA CORPORATION (JP) | 2005-02-09 | — | — | EP | disclosed |