Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | SDCBP | O00560 | 5/20 | 0.48 |
| ▸ | SDC2 | P34741 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445198 | 1.00 | FNTA (0.48) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL6447833 | 0.90 | EPHX2 (0.50) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL6447837 | 0.90 | EPHX2 (0.50) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL15870650 | 0.87 | PLA2G2A (0.53) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL8982548 | 0.86 | MME (0.41) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL10802294 | 0.86 | MME (0.41) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL8982544 | 0.86 | MME (0.41) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL232335 | 0.83 | NPSR1 (0.53) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL15623788 | 0.83 | PLA2G2A (0.56) | FNTAFNTBSDCBPSDC2NPSR1 | |
| SCHEMBL232334 | 0.83 | NPSR1 (0.53) | FNTAFNTBSDCBPSDC2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1991525-A1 | CYCLOHEXYLAMINO, BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | Serenex, Inc. (US) | 2008-11-19 | — | — | EP | disclosed |
| WO-2007101156-A1 | CYCLOHEXYLAMINO, BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | SERENEX, INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050130941-A1 | Methods of treating alzheimer's disease | BACE1, PSEN1, BACE2 | FNTA 3460/4885FNTB 2741/4885SDCBP 3079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.