Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TYMP | P19971 | 3/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131638 | 0.82 | LMNA (0.60) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| SCHEMBL5312329 | 0.81 | LMNA (0.70) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| SCHEMBL8432208 | 0.81 | LMNA (0.50) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| Potassium Ion SCHEMBL5317511 | 0.80 | LMNA (0.68) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| SCHEMBL15024639 | 0.79 | LMNA (0.80) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL6131639 | 0.79 | LMNA (0.56) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| SCHEMBL6131592 | 0.78 | CYP2C19 (0.53) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| SCHEMBL14499615 | 0.78 | LMNA (0.78) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| SCHEMBL15325016 | 0.78 | LMNA (0.61) | CYP2C19LMNATHRBCYP3A4CYP2D6 | |
| SCHEMBL942538 | 0.77 | LMNA (0.68) | CYP2C19LMNATHRBCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307226-B1 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | LANTHEUS MEDICAL IMAGING INC (US) | 2008-11-19 | — | — | EP | disclosed |