Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15743022 | 0.86 | SIRT3 (0.33) | ALDH1A1KDM4EMEN1KDM6BKDM4A | |
| Hydrochloric Acid SCHEMBL7435031 | 0.75 | MAPT (0.39) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL22418422 | 0.73 | SIRT3 (0.33) | ALDH1A1KDM4EMEN1KDM6BKDM4A | |
| SCHEMBL27771423 | 0.73 | — | — | |
| SCHEMBL27373630 | 0.72 | — | — | |
| SCHEMBL18328043 | 0.71 | CYP1A2 (0.34) | KDM4E | |
| SCHEMBL12324803 | 0.68 | — | — | |
| SCHEMBL31445919 | 0.68 | TNKS2 (0.35) | ALDH1A1KDM4EMAPTKMT2ATDP1 | |
| SCHEMBL31164764 | 0.65 | ALDH1A1 (0.32) | ALDH1A1KDM4EMEN1KDM6BKDM4A | |
| Acetic Acid SCHEMBL28280160 | 0.65 | KDM4C (0.33) | ALDH1A1KDM4EMEN1KDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725359-B | Substituted piperazine compound as well as application method and application thereof | 广东东阳光药业有限公司 | 2017-05-03 | — | — | CN | disclosed |
| EP-1996588-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | Torrent Pharmaceuticals Ltd (IN) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007100295-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | TORRENT PHARMACEUTICALS LTD (IN) | 2007-09-07 | — | — | WO | disclosed |