Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.36 |
| ▸ | GRM5 | P41594 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5306710 | 0.98 | RXFP1 (0.37) | RXFP1NPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL6217320 | 0.87 | GRM5 (0.43) | RXFP1KDM4EGRM5ALDH1A1MAPT | |
| SCHEMBL31309742 | 0.83 | MAPT (0.43) | RXFP1NPC1SMN1; SMN2RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL25416874 | 0.82 | RXFP1 (0.49) | RXFP1NPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL31309554 | 0.82 | MYC (0.41) | RXFP1NPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL6214030 | 0.81 | GRM5 (0.40) | NPC1SMN1; SMN2RAB9AKDM4EGRM5 | |
| SCHEMBL25417959 | 0.81 | GRM5 (0.38) | RXFP1NPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL4654873 | 0.80 | ALDH1A1 (0.41) | RXFP1NPC1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL31309600 | 0.77 | GRM5 (0.37) | RXFP1KDM4EGRM5ALDH1A1 | |
| SCHEMBL31309574 | 0.77 | RXFP1 (0.33) | RXFP1NPC1SMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996589-A1 | CHROMANE DERIVATIVES | RaQualia Pharma Inc (JP) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107827-A1 | CHROMANE DERIVATIVES | RAQUALIA PHARMA INC. (JP) | 2007-09-27 | — | — | WO | disclosed |