Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.35 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL294375 | 0.86 | NAPRT (0.50) | TDP1NAPRTTSHRCYP1A2CYP3A4 | |
| Pyrazine SCHEMBL2649926 | 0.86 | KDM4E (0.48) | TDP1NAPRTTSHRCYP1A2CYP3A4 | |
| Pyridine SCHEMBL27474885 | 0.84 | CYP1A2 (0.53) | TDP1NAPRTTSHRCYP1A2CYP3A4 | |
| Benzene SCHEMBL27433216 | 0.83 | CYP1A2 (0.44) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| Pyridine SCHEMBL10974779 | 0.82 | NAPRT (0.45) | TDP1NAPRTTSHRCYP1A2CYP3A4 | |
| Pyridine SCHEMBL10980010 | 0.80 | NAPRT (0.43) | TDP1NAPRTTSHRCYP1A2CYP3A4 | |
| Benzene SCHEMBL27907891 | 0.80 | CYP1A2 (0.41) | TSHRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| Pyridine SCHEMBL1164077 | 0.77 | NAPRT (0.60) | TDP1NAPRTTSHRCYP1A2CYP3A4 | |
| Pyridine SCHEMBL9065525 | 0.77 | NAPRT (0.60) | TDP1NAPRTTSHRCYP1A2CYP3A4 | |
| Pyridine SCHEMBL1070164 | 0.77 | NAPRT (0.60) | TDP1NAPRTTSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108978-A | Pyridine formyl hydrazine plant antifungal drugs | 西北农林科技大学 | 2022-09-27 | — | — | CN | claimed |
| CN-113861194-B | Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof | 英维沃化工科技(广州)有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-113861194-A | Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof | 英维沃化工科技(广州)有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-110294742-B | Fused ring ASK1 inhibitor and application thereof | 山东轩竹医药科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113861194-B | Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof | 英维沃化工科技(广州)有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-109311864-B | Heteroaryl substituted pyridines and methods of use | 艾伯维公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114423766-A | Penicilliane derivatives for the treatment of bacterial infections | 丹诺医药(苏州）有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-110357810-B | 2-pyridine formyl hydrazine Schiff base hypochloric acid fluorescent probe and preparation method and application thereof | 南京林业大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-113861194-A | Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof | 英维沃化工科技(广州)有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-112313224-A | ATF6 inhibitors and uses thereof | 黑带医疗有限责任公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-108137545-B | Triazole agonists of the APJ receptor | 美国安进公司 | 2020-09-22 | — | — | CN | disclosed |
| EP-1575921-B1 | PROCESS FOR THE SYNTHESIS OF ISONICOTINIC ACID HYDRAZIDE | COUNCIL SCIENT IND RES (IN) | 2008-12-03 | — | — | EP | disclosed |
| EP-1575921-A1 | PROCESS FOR THE SYNTHESIS OF ISONICOTINIC ACID HYDRAZIDE | Council of Scientific and Industrial Research (IN) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056778-A1 | PROCESS FOR THE SYNTHESIS OF ISONICOTINIC ACID HYDRAZIDE | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-07-08 | — | — | WO | disclosed |
| US-6734309-B1 | Process for the synthesis of isonicotinic acid hydrazide | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-05-11 | — | — | US | disclosed |