Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ECE1 | P42892 | 9/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655389 | 0.92 | MAOB (0.47) | MAOBECE1F10PTGDR2EPHX2 | |
| SCHEMBL4655386 | 0.90 | ECE1 (0.51) | MAOBECE1F10CCR2PTGDR2 | |
| SCHEMBL4656270 | 0.90 | F10 (0.46) | MAOBECE1F10CCR2 | |
| SCHEMBL3579347 | 0.88 | ECE1 (0.51) | MAOBECE1F10CCR2PTGDR2 | |
| SCHEMBL4655292 | 0.88 | MAOB (0.50) | MAOBECE1F10CCR2PTGDR2 | |
| SCHEMBL4655266 | 0.85 | ECE1 (0.56) | MAOBECE1F10PTGDR2 | |
| SCHEMBL4655318 | 0.85 | ECE1 (0.51) | MAOBECE1PTGDR2EPHX2PPARG | |
| SCHEMBL4655390 | 0.85 | MAOB (0.50) | MAOBECE1CCR2PTGDR2PPARG | |
| SCHEMBL4655298 | 0.85 | ECE1 (0.49) | MAOBECE1F10EPHX2PPARG | |
| SCHEMBL2811907 | 0.84 | MAOB (0.57) | MAOBECE1F10PTGDR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101010297-B | N- (1H-indolyl) -1H-indole-2-carboxamide derivatives, their preparation and their pharmaceutical use | SANOFI AVENTIS | 2011-07-27 | — | — | CN | claimed |
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |