Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4656158 | 0.91 | MAOB (0.46) | KDM4EMEN1LMNAMAPTKMT2A | |
| SCHEMBL4655294 | 0.90 | MAOB (0.48) | F10MAOBCCR2ECE1 | |
| SCHEMBL4655400 | 0.89 | PPARG (0.49) | F10MAPTCCR2ABCB1 | |
| SCHEMBL4655353 | 0.89 | ABCB1 (0.48) | F10KDM4EMEN1LMNAMAPT | |
| SCHEMBL4655389 | 0.89 | MAOB (0.47) | F10MAOBNOTUMECE1TP53 | |
| SCHEMBL4655386 | 0.87 | ECE1 (0.51) | F10MAOBCCR2NOTUMECE1 | |
| SCHEMBL3579347 | 0.87 | ECE1 (0.51) | F10MAOBCCR2NOTUMABCB1 | |
| SCHEMBL4655292 | 0.87 | MAOB (0.50) | F10KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4655329 | 0.85 | ECE1 (0.49) | F10KDM4ELMNAMAPTMAOB | |
| SCHEMBL4655397 | 0.85 | MAOB (0.48) | F10KDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776340-B1 | N-(1H-INDOLYL)-H-INDOLE-2-CARB0XAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2008-12-03 | — | — | EP | claimed |