Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL28371833 | 0.97 | TSHR (0.67) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Mucic Acid SCHEMBL28572245 | 0.87 | TSHR (0.53) | TSHRTP53CYP2C9PDE4ACYP2C19 | |
| Cadaverine Tartrate SCHEMBL31427568 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL1431070 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Tartaric Acid SCHEMBL29430365 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL22768 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL116846 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Tartaric Acid SCHEMBL5762 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL1062721 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL848 | 0.84 | TSHR (1.00) | TSHRTP53CYP2C9PDE4ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102020785-B | Compatilizer, application thereof in polyphenyleneoxide/nylon alloy and preparation method of polyphenyleneoxide/nylon alloy | UNIV HEBEI SCIENCE & TECH | 2013-02-13 | — | — | CN | claimed |
| EP-1143924-B2 | EXOTHERMIC EFFERVESCENT COMPOSITION FOR IMPROVED FRAGRANCE DISPERSION | PHYZZ INC (US) | 2008-11-26 | — | — | EP | claimed |
| EP-1143924-B1 | EXOTHERMIC EFFERVESCENT COMPOSITION FOR IMPROVED FRAGRANCE DISPERSION | PHYZZ INC (US) | 2005-10-26 | — | — | EP | claimed |
| CN-108815034-A | A kind of cosmetic composition of careful pore | 佛山文森特知识产权服务有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-102307976-A | Lubricating composition containing a compound derived from a hydroxycarboxylic acid | LUBRIZOL CORP | 2012-01-04 | — | — | CN | disclosed |
| EP-0088328-B1 | OXIDATION CATALYST, IN PARTICULAR FOR THE PREPARATION OF METHYACRYLIC ACID BY THE VAPOUR PHASE OXIDATION OF METHACROLEIN | BASF Aktiengesellschaft (DE) | 1986-07-30 | — | — | EP | disclosed |
| EP-0088328-A2 | Oxidation catalyst, in particular for the preparation of methyacrylic acid by the vapour phase oxidation of methacrolein | BASF Aktiengesellschaft (DE) | 1983-09-14 | — | — | EP | disclosed |
| US-4228033-A | USED IN STEAM REFORMING, CATALYTIC CRACKING OR OXIDATION OF HYDROCARBONS OR ALKANOLS | OSAKA GAS COMPANY, LIMITED (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4190554-A | DECARBONIZATION, DESULFURIZATION | OSAKA GAS COMPANY, LTD. (JP) | 1980-02-26 | — | — | US | disclosed |