Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 7/20 | 0.55 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.55 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.55 |
| ▸ | GGH | Q92820 | 1/20 | 0.47 |
| ▸ | GGT1 | P19440 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GRM8 | O00222 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2450582 | 1.00 | FOLH1 (0.55) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL8140077 | 0.90 | FOLH1 (0.53) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL141783 | 0.89 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL29356795 | 0.89 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL8768068 | 0.89 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL8769194 | 0.89 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL27868855 | 0.88 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL1286834 | 0.88 | FOLH1 (0.52) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL147131 | 0.87 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLAGGHGGT1 | |
| SCHEMBL27698275 | 0.87 | FOLH1 (0.59) | FOLH1NAALAD2RIMKLAGGHGGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460710-A | Amino acid cationic lipid | 厦门赛诺邦格生物科技股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-105899515-B | Derivatives of uncialamycin, method of synthesis and use thereof as antitumor agents | 威廉马歇莱思大学 | 2020-01-14 | — | — | CN | disclosed |
| CN-106132456-B | Apparatus, solution and method for sample collection | 阿波根有限公司 | 2019-12-24 | — | — | CN | disclosed |
| EP-1392755-B1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | ASTELLAS PHARMA EUROP B V (NL) | 2008-12-03 | — | — | EP | disclosed |
| US-20040241222-A1 | Lipid-polymer-conjugates compositions | ASTELLAS PHARMA EUROPE B.V. (NL) | 2004-12-02 | — | — | US | disclosed |
| EP-1392755-A1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | YAMANOUCHI EUROPE B.V. (NL) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002098952-A1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | YAMANOUCHI EUROPE B.V. (NL) | 2002-12-12 | — | — | WO | disclosed |
| EP-1189971-A2 | FUNCTIONAL POLY-ALPHA-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION | UNIVERSITEIT GENT (BE) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000078791-A2 | FUNCTIONAL POLY-α-AMINOACID DERIVATIVES USEFUL FOR THE MODIFICATION OF BIOLOGICALLY ACTIVE MATERIALS AND THEIR APPLICATION | UNIVERSITEIT GENT (BE) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040241222-A1 | Lipid-polymer-conjugates compositions | PHOSPHO1, PARG, GLUL | FOLH1 108/4885NAALAD2 312/4885RIMKLA 360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.