SCHEMBL465569

SCHEMBL465569

Cc1cc(C)cc(CNC(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
TSHR P16473 1/20 0.48
CYP2C19 P33261 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.47
TPMT P51580 1/20 0.46
MAOB P27338 1/20 0.44
POLB P06746 3/20 0.44
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
KDM4E B2RXH2 2/20 0.42
NPC1 O15118 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HPGD P15428 2/20 0.42
TP53 P04637 1/20 0.42
RAB9A P51151 1/20 0.42
MMP13 P45452 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7526917 0.94 GAA (0.45) GAACYP1A2CYP2D6CYP2C9TSHR
SCHEMBL18051105 0.88 AKR1C3 (0.44) GAACYP1A2CYP2D6CYP2C9TSHR
SCHEMBL17117530 0.86 KMT2A (0.50) GAASMN1; SMN2MAOBPOLBKDM4E
SCHEMBL9622672 0.85 KDM4E (0.42) GAACYP1A2CYP2D6CYP2C9TSHR
SCHEMBL15304335 0.85 CYP2C9 (0.50) GAACYP1A2CYP2D6CYP2C9TSHR
SCHEMBL14672776 0.83 GAA (0.44) GAATSHRMAOBPOLBLMNA
SCHEMBL22709990 0.82 KMT2A (0.50) GAASMN1; SMN2MAOBPOLBKDM4E
SCHEMBL11308583 0.81 ALDH1A1 (0.51) GAASMN1; SMN2MAOBPOLBLMNA
SCHEMBL17109741 0.81 HDAC6 (0.51) GAASMN1; SMN2MAOBPOLBKDM4E
SCHEMBL20428059 0.81 ERCC1 (0.57) GAACYP2D6CYP2C9CYP2C19MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1722633-B1 Use of a insecticidal composition againt mosquitoes, namely for impregnation of mosquito nets INST RECH POUR LE DÉVELOPPEMENT IRD (FR) 2014-06-18 EP claimed
EP-2462805-A1 Formulations containing stabilised compounds containing iodine LANXESS Deutschland GmbH (DE) 2012-06-13 EP claimed
EP-1697578-B1 COMPOSITION FOR THE IMPREGNATION OF FIBERS, FABRICS AND NETTINGS IMPARTING A PROTECTIVE ACTIVITY AGAINST PESTS BASF SE (DE) 2011-08-31 EP claimed
US-20070122437-A1 Novel insecticide composition and use thereof particularly for impregnating mosquito nets, fly screens and the like INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (FR) 2007-05-31 US claimed
EP-1411764-B1 A FENCING DISEASE CONTROL TEXTILES APS (DK) 2004-12-29 EP claimed
US-4226883-A Carbamate derivatives and method for manufacture thereof YAMAMOTO IZURU 1980-10-07 US claimed
WO-2024237275-A1 AGRICULTURAL AND HORTICULTURAL INSECT PEST CONTROL AGENT AND INSECT PEST CONTROL METHOD USING SAME クミアイ化学工業株式会社 2024-11-21 WO disclosed
CN-118302524-A High molecular weight modified dsRNA compositions 纳诺索尔公司 2024-07-05 CN disclosed
WO-2023149473-A1 MESOIONIC ARYL PYRIDAZINIUM DERIVATIVE OR SALT THEREOF, INSECTICIDE CONTAINING SAME, AND METHOD FOR USING SAME 日本農薬株式会社 2023-08-10 WO disclosed
WO-2023127808-A1 ARYLCYCLOHEXANEDIONE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME 株式会社ADEKA 2023-07-06 WO disclosed
WO-2023127805-A1 ARYL TETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, PESTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME 日本農薬株式会社 2023-07-06 WO disclosed
WO-2023127806-A1 ARYL TETRAHYDROPYRIDINE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 日本農薬株式会社 2023-07-06 WO disclosed
WO-2023127807-A1 ARYL CYCLOHEXANEDIONE DERIVATIVE OR SALT THEREOF, PEST CONTROL AGENT CONTAINING SAME, AND METHOD FOR USE THEREOF 株式会社ADEKA 2023-07-06 WO disclosed
US-5654299-A TREATING RESPIRATORY SYSTEM DISORDER (I.E. ASTHMA) WITH NEUROKININ 2 RECEPTOR ANTAGONIST ZENECA LIMITED (GB) 1997-08-05 US disclosed
EP-0630887-A1 4-(aryl-substituted)-piperidines as neurokinin receptor antagonists ZENECA LIMITED (GB) 1994-12-28 EP disclosed
EP-0358494-B1 Emulsifiable concentrate of a pesticide DOWELANCO (US) 1994-03-30 EP disclosed
EP-0256407-B1 INSECTICIDAL AGENT NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-03-06 EP disclosed
EP-0358494-A2 Emulsifiable concentrate of a pesticide DOWELANCO (US) 1990-03-14 EP disclosed
EP-0256407-A1 Insecticidal agent NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-02-24 EP disclosed
EP-0214546-A2 Insecticidal composition for use in agriculture and horticulture NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1987-03-18 EP disclosed