⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590525 | 0.97 | — | — | |
| SCHEMBL27762937 | 0.97 | — | — | |
| SCHEMBL6965014 | 0.79 | — | — | |
| SCHEMBL3736570 | 0.79 | — | — | |
| SCHEMBL16230562 | 0.77 | — | — | |
| SCHEMBL4657050 | 0.77 | — | — | |
| SCHEMBL8127007 | 0.77 | — | — | |
| SCHEMBL4657157 | 0.75 | — | — | |
| SCHEMBL6965925 | 0.75 | — | — | |
| SCHEMBL6968542 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57072974-A | — | — | None | — | — | JP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-10662205-B2 | Cyclic boronic acid ester derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190084999-A1 | CYCLIC BORONIC ACID ESTER DERIVATIVES AND THERAPEUTIC USES THEREOF | QPEX BIOPHARMA, INC. | 2019-03-21 | — | — | US | disclosed |
| WO-2016081297-A1 | CYCLIC BORONIC ACID ESTER DERIVATIVES AND THERAPEUTIC USES THEREOF | REMPEX PHARMACEUTICALS, INC. (US) | 2016-05-26 | — | — | WO | disclosed |
| EP-1996595-A2 | PROCESS FOR THE PREPARATION OF (1-OXA- OR l-THIA-)3- CEPHEM DERIVATIVES AND RELATED INTERMEDIATES | CARTHESIA s.a.s. DI EMANUELA MIGLIAVACCA & C. (IT) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007105253-A2 | PREPARATION OF (1-OXA- OR l-THIA-)3- CEPHEM DERIVATIVES | CARTHESIA S.A.S. DI EMANUELA MIGLIAVACCA & C. (IT) | 2007-09-20 | — | — | WO | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-4877783-A | β-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1989-10-31 | — | — | US | disclosed |
| US-4775670-A | BACTERICIDES, ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1988-10-04 | — | — | US | disclosed |
| US-4111978-A | CYANOALKYLTHIOACETIC ACID DERIVATIVES | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4103086-A | 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives | SMITHKLINE CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |
| US-4020057-A | 7β-Acyloxy cephalosporins | SMITHKLINE CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |
| US-3963711-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
| US-3963709-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-06-15 | — | — | US | disclosed |
| US-3957984-A | ANTIBACTERIAL, ANTIBIOTICS | SMITHKLINE CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
| US-3944546-A | BACTERICIDE | E. R. SQUIBB & SONS, INC. (US) | 1976-03-16 | — | — | US | disclosed |
| US-3932396-A | ANTIBIOTICS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932397-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1976-01-13 | — | — | US | disclosed |