⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968538 | 0.81 | — | — | |
| SCHEMBL11262277 | 0.79 | LMNA (0.64) | — | |
| SCHEMBL9453791 | 0.79 | LMNA (0.34) | — | |
| SCHEMBL9263707 | 0.76 | — | — | |
| E388 SCHEMBL28696 | 0.76 | LMNA (1.00) | — | |
| E388 SCHEMBL28962323 | 0.76 | LMNA (1.00) | — | |
| SCHEMBL4655740 | 0.75 | — | — | |
| SCHEMBL11465292 | 0.74 | TSHR (0.46) | — | |
| E388 SCHEMBL9715431 | 0.73 | LMNA (0.93) | — | |
| E388 SCHEMBL341724 | 0.73 | LMNA (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |