SCHEMBL465579

SCHEMBL465579

C[SiH](C)OCCCCCS

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
HDAC9 Q9UKV0 1/20 0.37
HDAC5 Q9UQL6 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2336043 1.00 HDAC3 (0.37) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL1954964 0.97
SCHEMBL4454679 0.89
SCHEMBL6572978 0.78
SCHEMBL382082 0.77
SCHEMBL12311052 0.76
SCHEMBL7895514 0.76 THRB (0.44)
SCHEMBL1054429 0.76 THRB (0.44)
SCHEMBL8598989 0.76 THRB (0.44)
SCHEMBL6891701 0.76 THRB (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113710718-A Stable silane-modified polymer compositions and methods 迈图高新材料公司 2021-11-26 CN claimed
CN-108137772-B Process for preparing silylated polymers with low color and color stability 莫门蒂夫性能材料股份有限公司 2021-06-29 CN claimed
CN-108012542-B Process for preparing silylated polymers using a back-mixing step 莫门蒂夫性能材料股份有限公司 2021-02-19 CN claimed
EP-1874840-B1 SILYLATED POLYMER DERIVED FROM BUTADIENE AND SOLVENT-RESISTANT PRESSURE SENSITIVE ADHESIVE COMPOSITION CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2020-06-03 EP claimed
EP-2231740-B1 MOISTURE-CURABLE SILYLATED POLYUREA AND ADHESIVE, SEALANT AND COATING COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2011-08-24 EP claimed
EP-4711518-A1 COATED FIBERS AND MOLDED BODY USING SAME Kuraray Co., Ltd. (JP) 2026-03-18 EP disclosed
US-20250376566-A1 SURFACE-MODIFIED FIBERS, REINFORCING FIBERS, AND MOLDED ARTICLE USING SAME KURARAY CO., LTD. (JP) 2025-12-11 US disclosed
EP-4032915-B1 CONJUGATED DIENE GRAFT POLYMER AND METHOD FOR PRODUCING THE SAME KURARAY CO (JP) 2025-11-05 EP disclosed
US-12460111-B2 Reinforcing fibers and production method therefor, and molded article using same KURARAY CO., LTD. (JP) 2025-11-04 US disclosed
US-12435195-B2 Surface-modified fibers, reinforcing fibers, and molded article using same KURARAY CO., LTD. (JP) 2025-10-07 US disclosed
US-12410264-B2 Conjugated diene graft polymer and method for producing the same KURARAY CO., LTD. (JP) 2025-09-09 US disclosed
US-12331178-B2 Rubber compositions KURARAY CO., LTD. (JP) 2025-06-17 US disclosed
US-20050032949-A1 Tire rubber composition comprising a coupling agent having a polythiosulfenamide function MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2005-02-10 US disclosed
US-20050032973-A1 Reactive polyurethane compositions with a low residual monomer content HENKEL AG & CO. KGAA (DE) 2005-02-10 US disclosed
EP-1474475-A1 RUBBER COMPOSITION FOR TYRE COMPRISING A COUPLING AGENT WITH POLYTHIOSUPLHENAMIDE FUNCTION Société de Technologie Michelin (FR) 2004-11-10 EP disclosed
EP-1456215-A1 ORGANOSILICON COMPOUNDS, ELASTOMER COMPOSITIONS AND ARTICLES Rhodia Chimie (FR) 2004-09-15 EP disclosed
EP-1434811-A1 REACTIVE POLYURETHANE COMPOSITIONS WITH LOW RESIDUAL MONOMER CONTENT Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP disclosed
WO-2003054075-A1 RUBBER COMPOSITION FOR TYRE COMPRISING A COUPLING AGENT WITH POLYTHIOSUPLHENAMIDE FUNCTION SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2003-07-03 WO disclosed
WO-2003053983-A1 ORGANOSILICON COMPOUNDS, ELASTOMER COMPOSITIONS AND ARTICLES RHODIA CHIMIE (FR) 2003-07-03 WO disclosed
WO-2003033562-A1 REACTIVE POLYURETHANE COMPOSITIONS WITH LOW RESIDUAL MONOMER CONTENT HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-24 WO disclosed