Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734089 | 0.77 | ALDH1A1 (0.36) | TSHR | |
| SCHEMBL506039 | 0.75 | — | — | |
| SCHEMBL6389618 | 0.71 | TSHR (0.31) | TSHR | |
| SCHEMBL4652993 | 0.70 | ALDH1A1 (0.54) | TSHR | |
| SCHEMBL9058713 | 0.67 | TSHR (0.33) | TSHR | |
| SCHEMBL19114388 | 0.67 | TSHR (0.33) | TSHR | |
| SCHEMBL4621590 | 0.65 | — | — | |
| SCHEMBL4654364 | 0.65 | TSHR (0.37) | TSHR | |
| SCHEMBL834918 | 0.63 | — | — | |
| SCHEMBL3632450 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1440155-B1 | LIPASE VARIANTS | BASF SE (DE) | 2008-11-12 | — | — | EP | disclosed |
| EP-1440155-A2 | LIPASE VARIANTS | BASF AKTIENGESELLSCHAFT (DE) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003035878-A2 | LIPASE VARIANTS | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-01 | — | — | WO | disclosed |
| EP-1069183-A2 | Immobilized lipase | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-17 | — | — | EP | disclosed |