Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 16/20 | 0.51 |
| ▸ | RARA | P10276 | 9/20 | 0.51 |
| ▸ | RARB | P10826 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL956315 | 0.88 | RARG (0.55) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4655852 | 0.88 | RARG (0.54) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4654752 | 0.86 | RARG (0.61) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4654839 | 0.86 | RARG (0.51) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4655897 | 0.85 | RARG (0.58) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4653634 | 0.84 | RARG (0.56) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4655882 | 0.84 | RARG (0.56) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4653486 | 0.84 | RARG (0.54) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL959752 | 0.83 | RARG (0.60) | RARGRARARARBKDM4EALDH1A1 | |
| SCHEMBL4654642 | 0.83 | RARG (0.55) | RARGRARARARBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692093-B1 | BIPHENYL DERIVATIVES USEFUL AS LIGANDS THAT ACTIVATE THE RAR RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2008-11-19 | — | — | EP | claimed |