Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 17/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 15/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070535 | 0.86 | ITGAV (0.50) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL6031988 | 0.80 | ITGAV (0.34) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL7392362 | 0.77 | ITGB3 (0.36) | ITGAVITGB3NR3C1ITGA2BITGB1 | |
| SCHEMBL1071117 | 0.77 | ITGAV (0.61) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1071135 | 0.77 | ITGAV (0.48) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1066573 | 0.76 | ITGAV (0.48) | ITGAVITGB3ITGA2B | |
| SCHEMBL1070634 | 0.76 | ITGAV (0.49) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL1070404 | 0.75 | ITGAV (0.49) | ITGAVITGB3ITGA2BITGB1ITGA5 | |
| SCHEMBL27577414 | 0.75 | KDM4E (0.36) | ITGAVITGB3 | |
| SCHEMBL1069186 | 0.74 | ITGAV (0.47) | ITGAVITGB3ITGA2BITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307226-B1 | VITRONECTIN RECEPTOR ANTAGONIST PHARMACEUTICALS | LANTHEUS MEDICAL IMAGING INC (US) | 2008-11-19 | — | — | EP | claimed |