Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 5/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898325 | 0.84 | ATM (0.60) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL12336762 | 0.84 | ATM (0.60) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL4900744 | 0.84 | ATM (0.60) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL13260263 | 0.84 | ATM (0.45) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL13162709 | 0.83 | ATM (0.51) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL4728727 | 0.83 | ATM (0.50) | ATMAPPCTSSCTSKAKT1 | |
| SCHEMBL2617222 | 0.83 | CTSS (0.53) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL683030 | 0.82 | CTSS (0.52) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL13919601 | 0.82 | ATM (0.49) | ATMAPPCTSSCTSKCTSB | |
| SCHEMBL14870407 | 0.82 | ATM (0.47) | ATMAPPCTSSCTSKAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006122-B1 | PHENETHYLAMINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-6255285-B1 | GASTROINTESTINAL DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-1006122-A1 | PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-06-07 | — | — | EP | disclosed |